Nucleation, growth and breakage phenomena in agitated wet granulation processes: a review

2001/06/01 by Simon M. Iveson, S.M. Iveson, James D. Litster +2 · 1,263 citations
Engineering · #Breakage #Composite material #Cyclone Separators and Fluid Dynamics #Economies of agglomeration #Engineering #Flow properties #Forensic engineering #Geotechnical engineering #Granular flow and fluidized beds #Granulation #Materials science #Mechanical engineering #Mechanics #Mineral Processing and Grinding #Nucleation #Process engineering #Thermodynamics #Wetting

paper · open access · doi:10.1016/s0032-5910(01)00313-8

published in Powder Technology 117(1-2), 3-39 (Elsevier BV)

openalex publication_date 2001/06/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Citations

• A theoretical model for the stick/bounce behaviour of adhesive, elastic-plastic spheres
• Quasi-static solid particle damage in brittle solids—I. Observations analysis and implications
• Analysis of Stresses and Strains Near the End of a Crack Traversing a Plate

Cited by

• Agglomeration in suspension of salicylic acid fine particles: Analysis of the wetting period and effect of the binder injection mode on the final agglomerate size
• Particle design via spherical agglomeration: A critical review of controlling parameters, rate processes and modelling
• Influence of process variables on internal particle structure in spray fluidized bed agglomeration
• Monte Carlo modeling of spray agglomeration in a cylindrical fluidized bed: From batch-wise to continuous processes
• Calibration of a DEM contact model for wet industrial granular materials
• Particle dynamics simulation of wet granulation in a rotating drum
• METAL-ORGANIC FRAMEWORKS IN RUSSIA: FROM THE SYNTHESIS AND STRUCTURE TO FUNCTIONAL PROPERTIES AND MATERIALS
• Dilatancy, jamming, and the physics of granulation
• Jamming and the onset of granulation in a model particle system
• Mesoscopic model for colloidal particles, powders, and granular solids
• Model-based analysis of high shear wet granulation from batch to continuous processes in pharmaceutical production – A critical review
• Effect of starting material particle size on its agglomeration behavior in high shear wet granulation. [europepmc]
• An energy-based population-balance approach to model granule growth and breakage in high-shear wet granulation processes. [europepmc]
• A novel fiber-optic photometer for in situ stability assessment of concentrated oil-in-water emulsions. [europepmc]
• Particle size, moisture, and fluidization variations described by indirect in-line physical measurements of fluid bed granulation. [europepmc]
• Formulation and evaluation of chitosan solid lipid nanoparticles of carbamazepine. [europepmc]
• Granulation techniques and technologies: recent progresses. [europepmc]
• A two-step approach for fluidized bed granulation in pharmaceutical processing: Assessing different models for design and control. [europepmc]
• Twin Screw Granulation: An Investigation of the Effect of Barrel Fill Level. [europepmc]
• Twin Screw Granulation: Effects of Properties of Primary Powders. [europepmc]
• Comprehensive Study of Intermediate and Critical Quality Attributes for Process Control of High-Shear Wet Granulation Using Multivariate Analysis and The Quality by Design Approach. [europepmc]
• Water Polishing improved controlled-release characteristics and fertilizer efficiency of castor oil-based polyurethane coated diammonium phosphate. [europepmc]
• Identifying Critical Binder Attributes to Facilitate Binder Selection for Efficient Formulation Development in a Continuous Twin Screw Wet Granulation Process. [europepmc]
• A Semi-Mechanistic Prediction of Residence Time Metrics in Twin Screw Granulation. [europepmc]
• Advances in Twin-Screw Granulation Processing. [europepmc]
• Process Analytical Technology Tools for Monitoring Pharmaceutical Unit Operations: A Control Strategy for Continuous Process Verification. [europepmc]
• Using a material database and data fusion method to accelerate the process model development of high shear wet granulation. [europepmc]
• Systematic Study of the Effects of High Shear Granulation Parameters on Process Yield, Granule Size, and Shape by Dynamic Image Analysis. [europepmc]
• Conceptualisation of an Efficient Particle-Based Simulation of a Twin-Screw Granulator. [europepmc]
• The effect of solid content on the rheological properties and microstructures of a Li-ion battery cathode slurry. [europepmc]
• A supraparticle-based biomimetic cascade catalyst for continuous flow reaction. [europepmc]
• The Effect of Mineral Admixtures and Fine Aggregates on the Characteristics of High-Strength Fiber-Reinforced Concrete. [europepmc]
• A Study on Aqueous Dispersing of Carbon Black Nanoparticles Surface-Coated with Styrene Maleic Acid (SMA) Copolymer. [europepmc]
• RAFT Polymer-Based Surfactants for Minerals Recovery. [europepmc]
• Investigating the Effects of Mixing Dynamics on Twin-Screw Granule Quality Attributes via the Development of a Physics-Based Process Map. [europepmc]
• Mesoporous Silica Nanoparticles as Drug Delivery Systems. [europepmc]