Model-based analysis of high shear wet granulation from batch to continuous processes in pharmaceutical production – A critical review

2013/09/20 by Ashish Kumar, Krist V. Gernaey, Thomas De Beer +1 · 126 citations
Engineering · Pharmacology, Toxicology and Pharmaceutics · #Breakage #Composite material #Computer science #Continuous production #Drug Solubulity and Delivery Systems #Engineering #Granular flow and fluidized beds #Granulation #Materials science #Mechanical engineering #Mineral Processing and Grinding #Process engineering #Unit operation

paper · pdf · doi:10.1016/j.ejpb.2013.09.013

published in European Journal of Pharmaceutics and Biopharmaceutics 85(3), 814-832 (Elsevier BV)

openalex publication_date 2013/09/20 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/30

Citations

• Data-driven Soft Sensors in the process industry
• Collision dynamics in fluidised bed granulators: A DEM-CFD study
• Discrete particle simulation of particulate systems: A review of major applications and findings
• Nucleation, growth and breakage phenomena in agitated wet granulation processes: a review
• A discrete numerical model for granular assemblies
• Solution of population balance equations using the direct quadrature method of moments