Indole-3-lactic acid, a metabolite of tryptophan, secreted by Bifidobacterium longum subspecies infantis is anti-inflammatory in the immature intestine

2020/01/16 by Di Meng, Eduardo Sommella, Emanuela Salviati +5 · 9 citations
Biochemistry, Genetics and Molecular Biology · Health Professions · Nursing · #Gut microbiota and health #Infant Health and Development #Infant Nutrition and Health

paper · doi:10.1038/s41390-019-0740-x

openalex publication_date 2020/01/16 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/27

Citations

• Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases

Cited by

• Genome-scale resources in the infant gut symbiont Bifidobacterium breve reveal genetic determinants of colonization and host-microbe interactions
• Microbes as medicine
• Heightened innate immunity may trigger chronic inflammation, fatigue and post-exertional malaise in ME/CFS
• Lacto-Fermented Fruits and Vegetables: Bioactive Components and Effects on Human Health
• Early-life colonization by aromatic-lactate-producing bifidobacteria lowers the risk of allergic sensitization
• Microbial-derived immunostimulatory small molecule augments anti-PD-1 therapy in lung cancer
• Heightened innate immunity may trigger chronic inflammation, fatigue and post-exertional malaise in ME/CFS
• Bifidobacterium species associated with breastfeeding produce aromatic lactic acids in the infant gut
• Indole Derivatives Biosynthesis in Bifidobacterium longum subsp. infantis and the Tryptophan Substrate Availability