Genome-scale resources in the infant gut symbiont Bifidobacterium breve reveal genetic determinants of colonization and host-microbe interactions

2025/03/10 by Anthony L. Shiver, Jiawei Sun, Rebecca Culver +35 · 2 voices · 2 citations
Biochemistry, Genetics and Molecular Biology · Agricultural and Biological Sciences · #Gut microbiota and health #Legume Nitrogen Fixing Symbiosis #Probiotics and Fermented Foods

paper · doi:10.1016/j.cell.2025.02.010

Citations

• Basic local alignment search tool
• Diet-induced extinctions in the gut microbiota compound over generations
• Indole-3-lactic acid, a metabolite of tryptophan, secreted by Bifidobacterium longum subspecies infantis is anti-inflammatory in the immature intestine

Cited by

• Machine Learning Reveals Quantitative Amino Acid Preferences in Bifidobacterium longum Growth
• Metabolic ecology of microbiomes: Nutrient competition, host benefits, and community engineering

Discussions

• Interested in the influence of the infant microbiome on health? Quickly interrogating non-model organisms using omic approaches? A new publication, describing genome-scale resources in bifidobacteri [bsky, 17 points, 3 comments]
• Cool systematic approach to study an important gut commensal. I think this is the right approach to studies microbiome from the bottom up. doi.org/10.1016/j.ce... [bsky, 0 points, 0 comments]