A revised airway epithelial hierarchy includes CFTR-expressing ionocytes

2018/07/31 by Daniel T. Montoro, Adam L. Haber, Moshe Biton +29 · 18 citations
Medicine · #Neonatal Respiratory Health Research #Asthma and respiratory diseases #Respiratory viral infections research

paper · doi:10.1038/s41586-018-0393-7

Cited by

• A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte
• Human distal lung maps and lineage hierarchies reveal a bipotent progenitor
• Physiology and pathophysiology of human airway mucus
• Updated epithelial barrier dysfunction in chronic rhinosinusitis: Targeting pathophysiology and treatment response of tight junctions
• Evidence of secondary Notch signaling within the rat small intestine
• An inflammasome-driven differentiation program in intestinal stem cells protects against Salmonella infection
• Recovery of human upper airway epithelium after smoking cessation is driven by a slow-cycling stem cell population and immune surveillance
• CFTR as a therapeutic target for severe lung infection
• Base editing and nanoparticle transfection of airway cell types essential for treatment of cystic fibrosis
• Single-cell susceptibility to viral infection is driven by variable cell states
• Dmxl1 Is an Essential Mammalian Gene that Is Required for V-ATPase Assembly and Function In Vivo
• Paired and solitary ionocytes in the zebrafish olfactory epithelium
• Single cell transcriptional analysis of human adenoids identifies molecular features of airway microfold cells
• A systems view of cellular heterogeneity: Unlocking the “wheel of fate”
• Specialized gas-exchange endothelium of the zebrafish gill
• Euclidean Distance Deflation Under High-Dimensional Heteroskedastic Noise
• Single-cell sequencing and organoids: applications in organ development and disease
• The H⁺-ATPase (V-ATPase): from proton pump to signaling complex in health and disease