A systems view of cellular heterogeneity: Unlocking the “wheel of fate”

2025/06/01 by Hourieh Movasat, Enzo Giacopino, Ali Shahdoost +4 · 1 voice
Biochemistry, Genetics and Molecular Biology · Medicine · #Gene Regulatory Network Analysis #Pancreatic function and diabetes #Pluripotent Stem Cells Research

paper · doi:10.1016/j.cels.2025.101300

crossref issued 2025/06/01 · crossref published 2025/06/01 · crossref published-print 2025/06/01 · openalex publication_date 2025/06/01 · crossref created 2025/06/04 · openalex created_date 2025/10/10 · crossref deposited 2025/11/08 · crossref indexed 2026/07/31 · openalex updated_date 2026/07/31

Citations

• A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte
• A revised airway epithelial hierarchy includes CFTR-expressing ionocytes
• Single-cell mapping of lineage and identity in direct reprogramming
• CellPhoneDB: inferring cell–cell communication from combined expression of multi-subunit ligand–receptor complexes
• Human organoids: model systems for human biology and medicine
• Generalizing RNA velocity to transient cell states through dynamical modeling
• Cells of the adult human heart
• Deciphering cell–cell interactions and communication from gene expression
• Charting cellular identity during human in vitro β-cell differentiation

Discussions

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