A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte

2018/07/31 by Lindsey W. Plasschaert, Rapolas Žilionis, Rayman Choo-Wing +5 · 12 citations
Medicine · #Neonatal Respiratory Health Research #Respiratory viral infections research #Inhalation and Respiratory Drug Delivery

paper · doi:10.1038/s41586-018-0394-6

Citations

• Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung
• A revised airway epithelial hierarchy includes CFTR-expressing ionocytes

Cited by

• Transfer learning enables predictions in network biology
• Human distal lung maps and lineage hierarchies reveal a bipotent progenitor
• Evidence of secondary Notch signaling within the rat small intestine
• Single-Cell and Spatial Transcriptomic Profiling Reveals Epithelial Functional States and Fibroblast Phenotypes in Hormone Therapy–Naïve Localized Prostate Cancer
• CFTR as a therapeutic target for severe lung infection
• Dictionary learning for integrative, multimodal and scalable single-cell analysis
• Base editing and nanoparticle transfection of airway cell types essential for treatment of cystic fibrosis
• Negative regulation of human IL-33 in endothelium during allergic airway inflammation
• Single cell transcriptional analysis of human adenoids identifies molecular features of airway microfold cells
• A systems view of cellular heterogeneity: Unlocking the “wheel of fate”
• Specialized gas-exchange endothelium of the zebrafish gill
• The H⁺-ATPase (V-ATPase): from proton pump to signaling complex in health and disease