2004/11/03 by E. V. Zemlyanaya, Zemlyanaya, E. V., Mikhail A. Kiselev +5
Biochemistry, Genetics and Molecular Biology · Medicine · Physics and Astronomy · #Biological Physics (physics.bio-ph) #Chemical Physics (physics.chem-ph) #Erythrocyte Function and Pathophysiology #FOS: Physical sciences #Hemoglobin structure and function #Lipid Membrane Structure and Behavior #physics.bio-ph #physics.chem-ph
paper · pdf · doi:10.48550/arxiv.physics/0411029
18 pages, 3 figures, 2 tables; to be published in JCMASE
openalex publication_date 2004/11/03 · arxiv created 2004/12/08 · arxiv updated 2009/12/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
On the basis of the separated form-factor model, a code for fitting the small-angle neutron scattering spectra of the polydispersed vesicle population has been developed. Vesicle and membrane bilayer parameters are analyzed for various hierarchical models of the neutron scattering length density across the membrane. It is shown that hydration of vesicle can be described by a linear distribution function of water molecules. For the first time, the average radius and polydispersity of the vesicle population, thickness of the membrane bilayer, thickness of hydrophobic and hydrophilic parts of bilayer, and water distribution function have been calculated from the SANS experiment, without additional methods such as dynamic light scattering or freeze-fracture electron microscopy. The results, obtained at two different spectrometers, are discussed. The appropriate conditions of the SANS experiment on vesicles are formulated as a necessity to collect the SANS curve in the region of scattering vectors from qmin=0.0033 1/angstrom to qmax=0.56 1/angstrom.