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Lattice analogy of area-difference elasticity model for lipid-detergent bilayer vesiculation

2006/04/02 by L. V. Elnikova, Elnikova, L. V.
Chemistry · Biochemistry, Genetics and Molecular Biology · Physics and Astronomy · #Surfactants and Colloidal Systems #Lipid Membrane Structure and Behavior #Force Microscopy Techniques and Applications

paper · pdf · doi:10.48550/arxiv.cond-mat/0604021

Abstract

The vesiculation process was examined in the lipid-detergent solution (dimyristoyl-sn-glycero-phoshatidylcholine/octaethylleneglycol n-dodecyl ether/water), using small-angle neutron scattering experiments \cite1. When observing vesiculation proceeds from rod-like micelles to unilamellar vesicles, the transformation is induced by jump-like temperature increase and a monotonic increase in detergent concentration. Our numerical estimations of the vesicle shape parameters (the elasticity coefficients and its fraction on a macroscopic scale) are based upon the area-difference elasticity model \cite2, 3. Thus, we composed the numerical Monte Carlo method, which connects the macroscopic and microscopic scales by the concept of self-avoiding random surfaces.

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