Characterization of the Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 ADX88178 in Rodent Models of Neuropsychiatric Disorders

2014/06/20 by Mikhail Kalinichev, Emmanuel Le Poul, Christelle Boléa +16 · 1 citation
Neuroscience · Biochemistry, Genetics and Molecular Biology · Psychology · #Neuroscience and Neuropharmacology Research #Receptor Mechanisms and Signaling #Neuroendocrine regulation and behavior

paper · pdf · doi:10.1124/jpet.114.214437

Citations

• A Potent and Selective Metabotropic Glutamate Receptor 4 Positive Allosteric Modulator Improves Movement in Rodent Models of Parkinson's Disease
• Recent advances in the phencyclidine model of schizophrenia

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• Effect of the mGlu4 positive allosteric modulator ADX-88178 on parkinsonism, psychosis-like behaviours and dyskinesia in the MPTP-lesioned marmoset