Biosynthesis and biotechnological production of statins by filamentous fungi and application of these cholesterol-lowering drugs

2002/04/01 by M. Manzoni, M. Rollini · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Aspergillus terreus #Atorvastatin #Biochemistry #Biology #Biosynthesis #Chemistry #Cholesterol #Coenzyme A #Enzyme #Fluvastatin #HMG-CoA reductase #Lovastatin #Microbial Metabolism and Applications #Microbial Natural Products and Biosynthesis #Pharmacology #Plant biochemistry and biosynthesis #Polyketide #Pravastatin #Reductase #Simvastatin #Statin

paper · doi:10.1007/s00253-002-0932-9

crossref issued 2002/04/01 · crossref published 2002/04/01 · crossref published-print 2002/04/01 · openalex publication_date 2002/04/01 · crossref created 2003/02/13 · openalex created_date 2016/06/24 · crossref deposited 2019/05/24 · openalex updated_date 2026/07/31 · crossref indexed 2026/07/31

Citations

• Modulation of Polyketide Synthase Activity by Accessory Proteins During Lovastatin Biosynthesis
• Monacolin K, a new hypocholesterolemic agent that specifically inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase.
• ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogensis produced by Penicillium citrinum.
• Monacolin K, a new hypocholesterolemic agent produced by a Monascus species.

Cited by

• Fungus [wikipedia]