Advances in CLIP Technologies for Studies of Protein-RNA Interactions

2018/02/01 by Flora Lee, Flora C.Y. Lee, Jernej Ule · 3 citations
Biochemistry, Genetics and Molecular Biology · #Biology #Computational biology #Gene #Gene expression #Genetics #Immunoprecipitation #RNA #RNA Research and Splicing #RNA and protein synthesis mechanisms #RNA modifications and cancer #RNA-binding protein #Transcriptome

paper · pdf · doi:10.1016/j.molcel.2018.01.005

crossref issued 2018/02/01 · crossref published 2018/02/01 · crossref published-print 2018/02/01 · openalex publication_date 2018/02/01 · crossref created 2018/02/01 · crossref deposited 2020/05/18 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01 · crossref indexed 2026/08/04

Citations

• Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome
• Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis
• HITS-CLIP yields genome-wide insights into brain alternative RNA processing
• FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
• Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP
• iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution
• 4-thiouridine inhibits rRNA synthesis and causes a nucleolar stress response
• Analysis of CLIP and iCLIP methods for nucleotide-resolution studies of protein-RNA interactions
• Evidence for reassociation of RNA-binding proteins after cell lysis: Implications for the interpretation of immunoprecipitation analyses
• A majority of m6A residues are in the last exons, allowing the potential for 3′ UTR regulation
• Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)
• sCLIP—an integrated platform to study RNA–protein interactomes in biomedical research: identification of CSTF2tau in alternative processing of small nuclear RNAs

Cited by

• Nucleotide-amino acid π-stacking interactions initiate photo cross-linking in RNA-protein complexes
• CLIP and complementary methods
• Cross-linking immunoprecipitation [wikipedia]