Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)

2016/03/28 by Eric L Van Nostrand, Eric L. Van Nostrand, Gabriel A. Pratt +18 · 6 citations
Biochemistry, Genetics and Molecular Biology · #Binding site #Biology #Computational biology #Gene #Gene expression #Genetics #Immunoprecipitation #RNA #RNA Research and Splicing #RNA and protein synthesis mechanisms #RNA modifications and cancer #RNA-binding protein #Ribonucleoprotein #Transcriptome

paper · doi:10.1038/nmeth.3810

crossref issued 2016/03/28 · crossref published 2016/03/28 · crossref published-online 2016/03/28 · openalex publication_date 2016/03/28 · crossref created 2016/03/28 · crossref published-print 2016/06/01 · crossref deposited 2022/03/21 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01 · crossref indexed 2026/08/06

Citations

• FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
• Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP
• Measuring reproducibility of high-throughput experiments
• iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution

Cited by

• sCLIP—an integrated platform to study RNA–protein interactomes in biomedical research: identification of CSTF2tau in alternative processing of small nuclear RNAs
• Data Science Issues in Studying Protein–RNA Interactions with CLIP Technologies
• Computational analysis of CLIP-seq data
• Advances in CLIP Technologies for Studies of Protein-RNA Interactions
• CLIP and complementary methods
• Cross-linking immunoprecipitation [wikipedia]