Developmental validation of the HIrisPlex system: DNA-based eye and hair colour prediction for forensic and anthropological usage

2014/01/03 by Susan Walsh, Lakshmi Chaitanya, Lindy Clarisse +11 · 5 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #Computational biology #Computer science #Forensic science #Genetics #Herpesvirus Infections and Treatments #Skin Protection and Aging #melanin and skin pigmentation

paper · doi:10.1016/j.fsigen.2013.12.006

openalex publication_date 2014/01/03 · crossref created 2014/01/03 · crossref issued 2014/03/01 · crossref published 2014/03/01 · crossref published-print 2014/03/01 · crossref deposited 2020/05/11 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/05 · crossref indexed 2026/08/06

Citations

• A Three–Single-Nucleotide Polymorphism Haplotype in Intron 1 of OCA2 Explains Most Human Eye-Color Variation
• IrisPlex: A sensitive DNA tool for accurate prediction of blue and brown eye colour in the absence of ancestry information
• Variants of the melanocyte–stimulating hormone receptor gene are associated with red hair and fair skin in humans
• Digital Quantification of Human Eye Color Highlights Genetic Association of Three New Loci
• Three Genome-wide Association Studies and a Linkage Analysis Identify HERC2 as a Human Iris Color Gene
• DNA-based prediction of human externally visible characteristics in forensics: Motivations, scientific challenges, and ethical considerations
• Genetic determinants of hair, eye and skin pigmentation in Europeans
• Blue eye color in humans may be caused by a perfectly associated founder mutation in a regulatory element located within the HERC2 gene inhibiting OCA2 expression
• Eye color and the prediction of complex phenotypes from genotypes

Cited by

• Forensic DNA Phenotyping: Predicting human appearance from crime scene material for investigative purposes
• A Common Genetic Origin for Early Farmers from Mediterranean Cardial and Central European LBK Cultures
• Genetic ancestry changes in Stone to Bronze Age transition in the East European plain
• Early Neolithic genomes from the eastern Fertile Crescent
• DNA phenotyping [wikipedia]