Genetic determinants of hair, eye and skin pigmentation in Europeans

2007/10/21 by Patrick Sulem, Daniel F Gudbjartsson, Daníel F. Guðbjartsson +38 · 9 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Acne and Rosacea Treatments and Effects #Biology #Eye color #Gene #Genetics #Genome-wide association study #Genotype #Single-nucleotide polymorphism #Skin Protection and Aging #Skin color #melanin and skin pigmentation

paper · doi:10.1038/ng.2007.13

crossref issued 2007/10/21 · crossref published 2007/10/21 · crossref published-online 2007/10/21 · openalex publication_date 2007/10/21 · crossref created 2007/10/21 · crossref published-print 2007/12/01 · crossref deposited 2023/05/18 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28 · crossref indexed 2026/08/06

Citations

• Skin pigmentation, biogeographical ancestry and admixture mapping
• Signatures of Positive Selection in Genes Associated with Human Skin Pigmentation as Revealed from Analyses of Single Nucleotide Polymorphisms
• Variants of the melanocyte–stimulating hormone receptor gene are associated with red hair and fair skin in humans
• Eye colour: portals into pigmentation genes and ancestry
• The Genetics of Sun Sensitivity in Humans
• European Population Substructure: Clustering of Northern and Southern Populations
• Evidence for Variable Selective Pressures at MC1R
• SLC24A5, a Putative Cation Exchanger, Affects Pigmentation in Zebrafish and Humans
• Major locus for red hair color linked to MNS blood groups on chromosome 4
• Genetic Signatures of Strong Recent Positive Selection at the Lactase Gene
• The Validity and Practicality of Sun-Reactive Skin Types I Through VI

Cited by

• Interactions Between HERC2, OCA2 and MC1R May Influence Human Pigmentation Phenotype
• Direct evidence for positive selection of skin, hair, and eye pigmentation in Europeans during the last 5,000 y
• IrisPlex: A sensitive DNA tool for accurate prediction of blue and brown eye colour in the absence of ancestry information
• The HIrisPlex-S system for eye, hair and skin colour prediction from DNA: Introduction and forensic developmental validation
• DNA-based prediction of human externally visible characteristics in forensics: Motivations, scientific challenges, and ethical considerations
• Developmental validation of the HIrisPlex system: DNA-based eye and hair colour prediction for forensic and anthropological usage
• Forensic DNA Phenotyping: Predicting human appearance from crime scene material for investigative purposes
• Prediction of eye color in the Slovenian population using the IrisPlex SNPs
• Eye color [wikipedia]