DNA-based prediction of human externally visible characteristics in forensics: Motivations, scientific challenges, and ethical considerations

2009/02/26 by Manfred Kayser, Peter M. Schneider · 4 citations
Biochemistry, Genetics and Molecular Biology · Psychology · #Biology #Computer science #Crime scene #Criminal investigation #Criminology #DNA #DNA profiling #Forensic and Genetic Research #Genetics #Molecular Biology Techniques and Applications #Physics #Psychology #Race, Genetics, and Society #Sample (material) #Suspect

paper · doi:10.1016/j.fsigen.2009.01.012

openalex publication_date 2009/02/26 · crossref created 2009/02/26 · crossref issued 2009/06/01 · crossref published 2009/06/01 · crossref published-print 2009/06/01 · crossref deposited 2021/10/02 · openalex created_date 2025/10/10 · crossref indexed 2026/07/24 · openalex updated_date 2026/08/01

Citations

• A Three–Single-Nucleotide Polymorphism Haplotype in Intron 1 of OCA2 Explains Most Human Eye-Color Variation
• Signatures of Positive Selection in Genes Associated with Human Skin Pigmentation as Revealed from Analyses of Single Nucleotide Polymorphisms
• Variants of the melanocyte–stimulating hormone receptor gene are associated with red hair and fair skin in humans
• Sizing up human height variation
• Three Genome-wide Association Studies and a Linkage Analysis Identify HERC2 as a Human Iris Color Gene
• Heritability in the genomics era — concepts and misconceptions
• Genetic determinants of hair, eye and skin pigmentation in Europeans
• Worldwide Human Relationships Inferred from Genome-Wide Patterns of Variation
• Blue eye color in humans may be caused by a perfectly associated founder mutation in a regulatory element located within the HERC2 gene inhibiting OCA2 expression
• Pleiotropic effects of the melanocortin 1 receptor (MC1R) gene on human pigmentation
• Characterization of Melanocyte Stimulating Hormone Receptor Variant Alleles in Twins with Red Hair
• SLC24A5, a Putative Cation Exchanger, Affects Pigmentation in Zebrafish and Humans
• The Evolution of Human Skin and Skin Color
• Eye color and the prediction of complex phenotypes from genotypes

Cited by

• The HIrisPlex-S system for eye, hair and skin colour prediction from DNA: Introduction and forensic developmental validation
• Developmental validation of the HIrisPlex system: DNA-based eye and hair colour prediction for forensic and anthropological usage
• Forensic DNA Phenotyping: Predicting human appearance from crime scene material for investigative purposes
• DNA phenotyping [wikipedia]