Mutations in smooth muscle α-actin (ACTA2) lead to thoracic aortic aneurysms and dissections

2007/11/11 by Dong-Chuan Guo, Hariyadarshi Pannu, Van Tran-Fadulu +37 · 3 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Actin #Anatomy #Aorta #Aortic aneurysm repair treatments #Ascending aorta #Biology #Cardiomyopathy and Myosin Studies #Cell biology #Connective tissue disorders research #Contraction (grammar) #Endocrinology #Gene #Genetics #Internal medicine #Medicine #Missense mutation #Mutation #Myosin

paper · doi:10.1038/ng.2007.6

crossref issued 2007/11/11 · crossref published 2007/11/11 · crossref published-online 2007/11/11 · openalex publication_date 2007/11/11 · crossref created 2007/11/11 · crossref published-print 2007/12/01 · openalex created_date 2016/06/24 · crossref deposited 2023/05/18 · crossref indexed 2026/08/03 · openalex updated_date 2026/08/04

Citations

• The Crystal Structure of Uncomplexed Actin in the ADP State
• Actin-binding proteins – a unifying hypothesis
• At least six different actins are expressed in a higher mammal: An analysis based on the amino acid sequence of the amino-terminal tryptic peptide

Cited by

• The ascending aortic aneurysm: When to intervene?
• Mutations in Smooth Muscle Alpha-Actin (ACTA2) Cause Coronary Artery Disease, Stroke, and Moyamoya Disease, Along with Thoracic Aortic Disease
• Actin [wikipedia]