Chromosome Missegregation and Apoptosis in Mice Lacking the Mitotic Checkpoint Protein Mad2

2000/06/01 by Max Dobles, Vasco Liberal, Martin L Scott +3 · 4 citations
Biochemistry, Genetics and Molecular Biology · #Anaphase #Biology #Cell #Cell biology #Cell cycle #Cell cycle checkpoint #Cell division #Chromosome #Chromosome segregation #DNA Repair Mechanisms #G2-M DNA damage checkpoint #Genetics #Genomics and Chromatin Dynamics #Kinetochore #Mad2 #Microtubule and mitosis dynamics #Mitosis #Mitotic exit #Spindle apparatus #Spindle checkpoint

paper · pdf · doi:10.1016/s0092-8674(00)80875-2

crossref issued 2000/06/01 · crossref published 2000/06/01 · crossref published-print 2000/06/01 · openalex publication_date 2000/06/01 · crossref created 2004/05/11 · crossref deposited 2021/06/17 · openalex created_date 2025/10/10 · crossref indexed 2026/07/01 · openalex updated_date 2026/07/15

Citations

• CDC20 and CDH1 : A Family of Substrate-Specific Activators of APC-Dependent Proteolysis
• Budding Yeast Cdc20: A Target of the Spindle Checkpoint

Cited by

• Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma
• MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells
• Mitotic catastrophe: a mechanism for avoiding genomic instability
• Peter Karl Sorger [wikipedia]