Conformational diversity and protein evolution – a 60-year-old hypothesis revisited

2003/07/01 by Leo C. James, Dan S. Tawfik · 4 citations
Biochemistry, Genetics and Molecular Biology · Materials Science · #Enzyme Structure and Function #Protein Structure and Dynamics #RNA and protein synthesis mechanisms

paper · doi:10.1016/s0968-0004(03)00135-x

crossref issued 2003/07/01 · crossref published 2003/07/01 · crossref published-print 2003/07/01 · openalex publication_date 2003/07/01 · crossref created 2003/07/22 · crossref deposited 2019/03/17 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/03 · crossref indexed 2026/08/03

Citations

• Catalytic promiscuity and the evolution of new enzymatic activities
• ENZYME RECRUITMENT IN EVOLUTION OF NEW FUNCTION

Cited by

• The 'evolvability' of promiscuous protein functions
• A structural model of latent evolutionary potentials underlying neutral networks in proteins
• Prions as adaptive conduits of memory and inheritance
• Dan Tawfik [wikipedia]