2012/10/25 by Mohammad A. A. Fakhree, Somaieh Ahmadian, Vahid Panahi-Azar +3 · 45 citations
Chemical Engineering · Chemistry · Materials Science · #Analytical Chemistry and Chromatography #Aqueous solution #Atmospheric pressure #Chemical and Physical Properties in Aqueous Solutions #Chemistry #Chromatography #Crystallization and Solubility Studies #Hydroxybenzoic acid #Melting point #Methanol #Nuclear chemistry #Organic chemistry #Propanol #Salicylic acid #Solubility
paper · open access · doi:10.1021/je300980k
published in Journal of Chemical & Engineering Data 57(11), 3303-3307 (American Chemical Society)
openalex publication_date 2012/10/25 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
Solubility of 2-hydroxybenzoic acid (salicylic acid, with measured melting point of 432 K) in water, 1-propanol, 2-propanol, and 2-propanone was determined at (298.2 to 338.2) K and atmospheric pressure. Also, the solubility of salicylic acid in binary mixtures of 1-propanol (1) + water (2), 2-propanol (1) + water (2), and 2-propanone (1) + water (2) at 298.2 K and atmospheric pressure was investigated. Phase separation occurred in x 1 = 0.114, 0.167 of 1-propanol (1) + water (2) and x 1 = 0.171, 0.237 of 2-propanone (1) + water (2) mixtures. The van’t Hoff and Grant equations were used to correlate the solubility of salicylic acid in monosolvents at different temperatures. The solubility values of salicylic acid in binary mixtures of solvents were calculated using the Jouyban–Acree model ( J. Chem. Eng. Data 2009, 54, 1168–1170). The mean deviation was used as an error criterion. The overall mean deviation of correlated solubility data in monosolvents at different temperatures, and in mixed solvents at 298.2 K were 1.0 % and 8.3 %, respectively.