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Borders of Multiple Visual Areas in Humans Revealed by Functional Magnetic Resonance Imaging

1995/05/12 by Martin I. Sereno, Anders M. Dale, J.B. Reppas +5 · 17 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · Psychology · #Artificial intelligence #Computer science #Computer vision #Extrastriate cortex #Functional magnetic resonance imaging #Gaze #Magnetic resonance imaging #Medicine #Neural dynamics and brain function #Neuroscience #Psychology #Retinal Development and Disorders #Visual cortex #Visual field #Visual perception and processing mechanisms

paper · doi:10.1126/science.7754376

openalex publication_date 1995/05/12 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/06

Abstract

The borders of human visual areas V1, V2, VP, V3, and V4 were precisely and noninvasively determined. Functional magnetic resonance images were recorded during phase-encoded retinal stimulation. This volume data set was then sampled with a cortical surface reconstruction, making it possible to calculate the local visual field sign (mirror image versus non-mirror image representation). This method automatically and objectively outlines area borders because adjacent areas often have the opposite field sign. Cortical magnification factor curves for striate and extrastriate cortical areas were determined, which showed that human visual areas have a greater emphasis on the center-of-gaze than their counterparts in monkeys. Retinotopically organized visual areas in humans extend anteriorly to overlap several areas previously shown to be activated by written words.

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