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Propargyl Claisen rearrangement: allene synthesis and beyond

2012/10/04 by David Tejedor, Gabriela Méndez‐Abt, Leandro Cotos +1 · 1 citation
Chemistry · #Catalytic Alkyne Reactions #Synthetic Organic Chemistry Methods #Click Chemistry and Applications

paper · doi:10.1039/c2cs35311c

openalex publication_date 2012/10/04 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/22

Abstract

The propargyl Claisen rearrangement is a known protocol to gain access to functionalized allenes through the [3,3]-sigmatropic transformation of propargyl vinyl ethers. The correct use of appropriate propargyl vinyl ethers as starting materials coupled with suitable reaction conditions can aid in the development of new domino methodologies in which the allenes are valuable intermediates in route to a wide range of important classes of organic compounds.

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