Efficient Transformation of Methyl Propargyl Ethers into α,β-Unsaturated Ketones

1991/06/01 by Yukitoshi Fukuda, Kiitiro Utimoto

paper · doi:10.1246/bcsj.64.2013

crossref issued 1991/06/01 · crossref published 1991/06/01 · crossref published-print 1991/06/01 · crossref published-online 2006/06/07 · crossref created 2006/07/26 · crossref deposited 2024/01/19 · crossref indexed 2026/07/28

Abstract

Abstract Methyl propargyl ethers, obtained from carbonyl compounds by successive treatment with an acetylide and MeI, were easily converted to the corresponding α,β-unsaturated ketone by regioselective hydration of acetylenic moiety followed by elimination of methanol under the catalytic action of Au(III).

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