Flupirtine shows functional NMDA receptor antagonism by enhancing Mg 2+ block via activation of voltage independent potassium channels

1999/10/20 by J. Kornhuber, Johannes Kornhuber, S. Bleich +7 · 6 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Ion channel regulation and function #Neuroscience and Neuropharmacology Research #Pain Mechanisms and Treatments

paper · doi:10.1007/s007020050206

crossref issued 1999/10/20 · crossref published 1999/10/20 · crossref published-print 1999/10/20 · openalex publication_date 1999/10/20 · crossref created 2002/08/25 · openalex created_date 2016/06/24 · crossref deposited 2019/05/29 · crossref indexed 2026/02/27 · openalex updated_date 2026/07/23

Cited by

• Flupirtine, a re-discovered drug, revisited
• Positive reinforcing effects of flupirtine — Two case reports
• Flupirtine in Pain Management
• Flupirtine: pharmacology and clinical applications of a nonopioid analgesic and potentially neuroprotective compound
• Identification of New Functional Inhibitors of Acid Sphingomyelinase Using a Structure−Property−Activity Relation Model
• Analgesic [wikipedia]