2013/04/22 by Teruo Umemoto, Ahmad El-Awa · 1 citation
Pharmacology, Toxicology and Pharmaceutics · Chemistry · #Fluorine in Organic Chemistry #Synthesis and Reactivity of Heterocycles #Synthesis and Reactions of Organic Compounds
paper · doi:10.1002/047084289x.rf012.pub2
openalex publication_date 2013/04/22 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29
[107263-95-6] C6H5F4NO3S (MW 247.17) InChI = 1S/C5H5FN.CHF3O3S/c6-7-4-2-1-3-5-7;2-1(3,4)8(5,6)7/h1-5H;(H,5,6,7)/q+1;/p-1 InChIKey = JFZMMCYRTJBQQI-UHFFFAOYSA-M (fluorinating agent for many nucleophilic substrates) Physical Data: mp 185–187 °C. Solubility: sol polar solvents such as MeCN; 0.6 mg mL−1 in CH2Cl2; 1.7 mg mL−1 in THF; insol Et2O. Form Supplied in: white crystals; widely available. Analysis of Reagent Purity: 1H and 19F NMR, IR.2 Purification: recrystallization from MeCN–Et2O at rt.2 Handling, Storage, and Precautions: nonhygroscopic and thermally stable. The reagent should be stored in a dry atmosphere protected from light. Handle in a fume hood.