Nanobody-Mediated Dualsteric Engagement of the Angiotensin Receptor Broadens Biased Ligand Pharmacology

2023/12/21 by Nayara Braga Emídio, Nayara Braga Emidio, Brandi M. Small +3 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · #Agonist #Allosteric modulator #Allosteric regulation #Angiotensin II #Biochemistry #Chemistry #G protein-coupled receptor #Ligand (biochemistry) #Monoclonal and Polyclonal Antibodies Research #Neuropeptides and Animal Physiology #Partial agonist #Pharmacophore #Radioligand #Receptor #Receptor Mechanisms and Signaling #Stereochemistry

paper · pdf · doi:10.1124/molpharm.123.000797

openalex publication_date 2023/12/21 · crossref created 2023/12/21 · crossref issued 2024/03/01 · crossref published 2024/03/01 · crossref published-print 2024/03/01 · crossref deposited 2025/02/19 · openalex created_date 2025/10/10 · crossref indexed 2026/06/05 · openalex updated_date 2026/08/06

Citations

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Cited by

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Discussions

• So happy to share a link to a paper just published from my group for the first time on ChemSky 🧪. This was an awesome collaboration with Laura Wingler's group from Duke, which led to some unexpected [bsky, 0 points, 0 comments]