Ferroptosis: A Targetable Vulnerability for Melanoma Treatment

2025/01/09 by Meng Yu, Yu Meng, Qian Zhou +4 · 1 voice
Biochemistry, Genetics and Molecular Biology · Medicine · #Cancer, Lipids, and Metabolism #Ferroptosis and cancer prognosis #RNA modifications and cancer

paper · doi:10.1016/j.jid.2024.11.007

openalex publication_date 2025/01/09 · crossref created 2025/01/09 · crossref issued 2025/06/01 · crossref published 2025/06/01 · crossref published-print 2025/06/01 · openalex created_date 2025/10/10 · crossref deposited 2026/03/23 · crossref indexed 2026/07/03 · openalex updated_date 2026/07/22

Citations

• Glutathione: Overview of its protective roles, measurement, and biosynthesis
• Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma
• Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death
• Targeting apoptosis in cancer therapy
• The Roles of CD8+ T Cell Subsets in Antitumor Immunity
• The tumor microenvironment
• Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy
• Ferroptosis: molecular mechanisms and health implications
• Ferroptosis: mechanisms, biology and role in disease
• Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors
• CAMKK2 Defines Ferroptosis Sensitivity of Melanoma Cells by Regulating AMPK‒NRF2 Pathway
• Macrophage Polarization

Discussions

• A review by Yu Meng et al, "Ferroptosis: a targetable vulnerability for melanoma treatment" doi.org/10.1016/j.ji... #JIDJournal #dermscience #openaccess [bsky, 0 points, 0 comments]