CAMKK2 Defines Ferroptosis Sensitivity of Melanoma Cells by Regulating AMPK‒NRF2 Pathway

2021/07/07 by Sijia Wang, Xiuli Yi, Zhenjie Wu +7 · 27 citations
Medicine · Biochemistry, Genetics and Molecular Biology · #Ferroptosis and cancer prognosis #Cancer-related molecular mechanisms research #Cancer, Lipids, and Metabolism

paper · pdf · doi:10.1016/j.jid.2021.05.025

Citations

• Calcium-mediated cell death during myocardial reperfusion
• Glutathione metabolism in cancer progression and treatment resistance

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• Transcriptional Repression of Ferritin Light Chain Increases Ferroptosis Sensitivity in Lung Adenocarcinoma. [europepmc]
• Novel Photoinduced Squalene Cyclic Peroxide Identified, Detected, and Quantified in Human Skin Surface Lipids. [europepmc]
• Phosphocatalytic Kinome Activity Profiling of Apoptotic and Ferroptotic Agents in Multiple Myeloma Cells. [europepmc]
• Targeting CAMKK2 and SOC Channels as a Novel Therapeutic Approach for Sensitizing Acute Promyelocytic Leukemia Cells to All-Trans Retinoic Acid. [europepmc]
• Ferroptosis-Inducing Nanomedicine for Cancer Therapy. [europepmc]
• The Role of AMP-activated Protein Kinase in Oxytosis/Ferroptosis: Protector or Potentiator? [europepmc]
• Construction and Validation of a Ferroptosis-Related Prognostic Signature for Melanoma Based on Single-Cell RNA Sequencing. [europepmc]
• Acetyl-CoA synthetase 2(ACSS2): a review with a focus on metabolism and tumor development. [europepmc]
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• Targeting Wnt/β-Catenin Signaling Exacerbates Ferroptosis and Increases the Efficacy of Melanoma Immunotherapy via the Regulation of MITF. [europepmc]
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• Heme Oxygenase-1-Modified BMMSCs Activate AMPK-Nrf2-FTH1 to Reduce Severe Steatotic Liver Ischemia-Reperfusion Injury. [europepmc]
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• Ferroptosis as a promising therapeutic strategy for melanoma. [europepmc]
• The mechanism of ferroptosis and its related diseases. [europepmc]
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• Splicing neoantigen discovery with SNAF reveals shared targets for cancer immunotherapy. [europepmc]
• Nrf2 in human cancers: biological significance and therapeutic potential. [europepmc]
• Dapagliflozin improves diabetic kidney disease by inhibiting ferroptosis through β-hydroxybutyrate production. [europepmc]
• Ferroptosis-related signaling pathways in cancer drug resistance. [europepmc]
• 5-HT regulates resistance to aumolertinib by attenuating ferroptosis in lung adenocarcinoma. [europepmc]