UXS1 Knockdown Suppresses Cell Proliferation and Invasion in Hepatocellular Carcinoma by Inducing Ferroptosis via SLC7A11/GPX4 Pathway

2026/03/17 by Jun Lv, Kang Han, Fu-yuan Gan +3 · 1 voice
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Cancer, Lipids, and Metabolism #Ferroptosis and cancer prognosis #Immune cells in cancer

paper · doi:10.1007/s11596-026-00183-y

crossref issued 2026/03/17 · crossref published 2026/03/17 · crossref published-online 2026/03/17 · openalex publication_date 2026/03/17 · crossref created 2026/03/17 · openalex created_date 2026/03/18 · crossref published-print 2026/04/01 · crossref deposited 2026/04/28 · crossref indexed 2026/04/29 · openalex updated_date 2026/08/01

Citations

• The Chemistry of Reactive Oxygen Species (ROS) Revisited: Outlining Their Role in Biological Macromolecules (DNA, Lipids and Proteins) and Induced Pathologies
• ROS in hepatocellular carcinoma: What we know
• Silencing NCAPD3 Inhibits Tumor Growth and Metastasis in Hepatocellular Carcinoma by Suppressing PI3K-AKT Signalling Pathway

Discussions

• Findings from this study identify UXS1 as a prognostic #Biomarker in #HepatocellularCarcinoma, with knockdown suppressing #MalignantProgression through #Ferroptosis induction via the SLC7A11/#GPX4 axi [bsky, 0 points, 0 comments]