CRISPR-based diagnostics

2021/07/16 by Michael M. Kaminski, Omar O. Abudayyeh, Jonathan S. Gootenberg +2 · 14 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Advanced biosensing and bioanalysis techniques #CRISPR and Genetic Engineering #Mosquito-borne diseases and control

paper · pdf · doi:10.1038/s41551-021-00760-7

crossref issued 2021/07/16 · crossref published 2021/07/16 · crossref published-online 2021/07/16 · openalex publication_date 2021/07/16 · crossref created 2021/07/16 · crossref deposited 2024/12/11 · openalex created_date 2025/10/10 · crossref indexed 2026/07/30 · openalex updated_date 2026/07/30

Citations

• A method for the absolute quantification of cDNA using real-time PCR
• Intervening Sequences of Regularly Spaced Prokaryotic Repeats Derive from Foreign Genetic Elements
• Seed priming: the aftermath.
• Programmable CRISPR-responsive smart materials
• Virological assessment of hospitalized patients with COVID-2019
• A mountable toilet system for personalized health monitoring via the analysis of excreta
• CRISPR–Cas12-based detection of SARS-CoV-2

Cited by

• Bacteria as living biosensors for DNA
• Convergence of nanotechnology and CRISPR-based diagnostics
• Endophytic fungi as a source of antimicrobial compounds against emerging methicillin-resistant Staphylococcus aureus
• Accelerating Genetic Sensor Development, Scale-up, and Deployment Using Synthetic Biology
• SATCAS: A CRISPR/Cas13a-based simultaneous amplification and testing platform for one-pot RNA detection and SNPs distinguish in clinical diagnosis
• A Chimeric Photo-Controllable CRISPR/Cas12a System for Universal and Fast Diagnostics
• Unleashing high trans -substrate cleavage kinetics of Cas12a for nucleic acid diagnostics
• TracrRNA reprogramming enables direct PAM-independent detection of RNA with diverse DNA-targeting Cas12 nucleases
• Digital CRISPR-based diagnostics for quantification of Candida auris and resistance mutations
• RNA-triggered Cas12a3 cleaves tRNA tails to execute bacterial immunity
• Rapid, Amplification-free, RNA-based Uropathogen Detection With LbuCas13a
• Evolution of Point‐of‐Care Nucleic Acid Testing: From Amplification Chemistry to Intelligent and Data‐Driven Systems for Public Health
• Engineering delivery platforms for CRISPR-Cas and their applications in healthcare, agriculture and beyond
• SIMPLE: A One-Pot RPA-Cas12b Method for Single Nucleotide Variations Identification with an Expanded Scope and Clinical Applications