2021/12/09 by Fabio Juliá, Timothée Constantin, Daniele Leonori · 3 citations
Chemistry · Pharmacology, Toxicology and Pharmaceutics · #Radical Photochemical Reactions #Oxidative Organic Chemistry Reactions #Fluorine in Organic Chemistry
paper · doi:10.1021/acs.chemrev.1c00558
openalex created_date 2021/12/06 · openalex publication_date 2021/12/09 · openalex updated_date 2026/07/31
The halogen-atom transfer (XAT) is one of the most important and applied processes for the generation of carbon radicals in synthetic chemistry. In this review, we summarize and highlight the most important aspects associated with XAT and the impact it has had on photochemistry and photocatalysis. The organization of the material starts with the analysis of the most important mechanistic aspects and then follows a subdivision based on the nature of the reagents used in the halogen abstraction. This review aims to provide a general overview of the fundamental concepts and main agents involved in XAT processes with the objective of offering a tool to understand and facilitate the development of new synthetic radical strategies.