2023/03/29 by Weistenhöfer, Wobbeke, Michaelsen, Sandra, Schriever-Schwemmer, Gerlinde +3
#Arbeitsstoff #BAT value #BAT-Wert #Biologischer Arbeitsstoff-Toleranzwert #Biomonitoring #Entwicklungstoxizität #Ethylbenzene #Ethylbenzol #Gefahrstoff #Mandelic acid #Mandelsäure #Phenylethan #Phenylethane #Phenylglyoxylic acid #Phenylglyoxylsäure #Toxizität #Urin #biological tolerance value #biomonitoring #developmental toxicity #fruchtschädigende Wirkung #hazardous substance #occupational exposure #prenatal toxicity #toxicity #urine
paper · doi:10.34865/bb10041e8_1ad
In 2011, the German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area re-evaluated the maximum workplace concentration (MAK value) of ethylbenzene [100-41-4]. If the MAK value of 20 ml ethylbenzene/m3 (88 mg/m3) is observed, no prenatal toxic effects are to be expected. Therefore, ethylbenzene was classified in Pregnancy Risk Group C. In 2015, the biological tolerance value (BAT value) of 250 mg mandelic acid plus phenylglyoxylic acid/g creatinine was derived in correlation to the MAK value. Pregnancy Risk Group C is therefore similarly valid for the BAT value. In adherence with the BAT value of 250 mg mandelic acid plus phenylglyoxylic acid/g creatinine, no prenatal toxic effects are to be expected.