2023/03/29 by Weistenhöfer, Wobbeke, Michaelsen, Sandra, Schriever-Schwemmer, Gerlinde +3
#(1-Methylethyl)benzene #(1-Methylethyl)benzol #1-Hydroxycumene #1-Hydroxycumol #2-Phenyl-2-propanol #2-Phenylisopropanol #2-Phenylpropan #2-Phenylpropane #Arbeitsstoff #BAT value #BAT-Wert #Biologischer Arbeitsstoff-Toleranzwert #Biomonitoring #Cumene #Cumol #Dimethylphenylcarbinol #Dimethylphenylmethanol #Entwicklungstoxizität #Gefahrstoff #Isopropylbenzene (cumene) #Isopropylbenzol (Cumol) #Propan-2-ylbenzene #Propan-2-ylbenzol #Toxizität #Urin #biological tolerance value #biomonitoring #developmental toxicity #fruchtschädigende Wirkung #hazardous substance #occupational exposure #prenatal toxicity #toxicity #urine
paper · doi:10.34865/bb9882d8_1ad
In 2012, the German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area re-evaluated the maximum workplace concentration (MAK value) of isopropylbenzene (cumene) [98-82-8]. If the MAK value of 10 ml isopropylbenzene/m3 (50 mg/m3) is observed, no prenatal toxic effects are to be expected. Therefore, Pregnancy Risk Group C was confirmed. In 2013, the biological tolerance value (BAT value) of 10 mg 2-phenyl-2-propanol (after hydrolysis)/g creatinine was derived in correlation to the MAK value. Pregnancy Risk Group C is also similarly valid for the BAT value. In adherence with the BAT value of 10 mg 2-phenyl-2-propanol (after hydrolysis)/g creatinine, no prenatal toxic effects are to be expected.