2022/09/29 by Weistenhöfer, Wobbeke, Michaelsen, Sandra, Schriever-Schwemmer, Gerlinde +3
#1 #2-Hydroxyethoxyacetic acid #2-Hydroxyethoxyessigsäure #4-Dioxacyclohexan #4-Dioxacyclohexane #4-Dioxan #4-Dioxane #4-dioxin #Arbeitsstoff #BAT value #BAT-Wert #Biologischer Arbeitsstoff-Toleranzwert #Biomonitoring #Diethylendioxid #Diethylene dioxide #Entwicklungstoxizität #Gefahrstoff #Tetrahydro-1 #Toxizität #Urin #biological tolerance value #biomonitoring #developmental toxicity #fruchtschädigende Wirkung #hazardous substance #occupational exposure #p-Dioxan #p-Dioxane #prenatal toxicity #toxicity #urine
paper · doi:10.34865/bb12391e7_3ad
In 2018, the German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re-evaluated the maximum workplace concentration (MAK value) of 1,4-dioxane [ 123-91-1 ]. If the MAK value of 10 ml 1,4-dioxane/m 3 (37 mg/m 3 ) is not exceeded, prenatal toxic effects are not to be expected, so that Pregnancy Risk Group C was confirmed. In 2019, the biological tolerance value (BAT value) of 200 mg 2-hydroxyethoxyacetic acid/g creatinine was derived in correlation to the MAK value. Therefore, Pregnancy Risk Group C is also valid for the BAT value. Adhering to the BAT value of 200 mg 2-hydroxyethoxyacetic acid/g creatinine, prenatal toxic effects are not to be expected.