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1,4-Dichlorobenzene – Addendum: evaluation of a pregnancy risk group for the BAT value

2022/09/29 by Weistenhöfer, Wobbeke, Michaelsen, Sandra, Schriever-Schwemmer, Gerlinde +3
#1 #2 #4-Dichlorbenzol #4-Dichlorobenzene #5-Dichlorophenol #5-Dichlorphenol #Arbeitsstoff #BAT value #BAT-Wert #Biologischer Arbeitsstoff-Toleranzwert #Biomonitoring #Entwicklungstoxizität #Gefahrstoff #Toxizität #Urin #biological tolerance value #biomonitoring #developmental toxicity #fruchtschädigende Wirkung #hazardous substance #occupational exposure #p-Dichlorbenzol #p-Dichlorobenzene #prenatal toxicity #toxicity #urine

paper · doi:10.34865/bb10646e7_3ad

Abstract

In 2017, the German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re-evaluated the maximum workplace concentration (MAK value) of 1,4-dichlorobenzene [106-46-7]. If the MAK value of 2 ml 1,4-dichlorobenzene/m3 (12 mg/m3) is not exceeded, prenatal toxic effects are not to be expected. Therefore, 1,4-Dichlorobenzene was classified in Pregnancy Risk Group C. In 2019, the biological tolerance value (BAT value) of 10 mg 2,5-dichlorophenol/l urine was derived in correlation to the MAK value. Therefore, Pregnancy Risk Group C is also valid for the BAT value. Adhering to the BAT value of 10 mg 2,5-dichlorophenol/l urine, prenatal toxic effects are not to be expected.

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