2022/09/29 by Weistenhöfer, Wobbeke, Michaelsen, Sandra, Schriever-Schwemmer, Gerlinde +3
#Acetdimethylamide #Acetyldimethylamin #Arbeitsstoff #BAT value #BAT-Wert #Biologischer Arbeitsstoff-Toleranzwert #Biomonitoring #Dimethylacetamid #Dimethylacetamide #Entwicklungstoxizität #Essigsäuredimethylamid #Gefahrstoff #N #N-Dimethylacetamid #N-Dimethylacetamide #N-Dimethylethanamid #N-Dimethylethanamide #N-Hydroxymethyl-N-methylacetamid #N-Hydroxymethyl-N-methylacetamide #N-Methylacetamid #N-Methylacetamide #Toxizität #Urin #biological tolerance value #biomonitoring #developmental toxicity #fruchtschädigende Wirkung #hazardous substance #occupational exposure #prenatal toxicity #toxicity #urine
paper · doi:10.34865/bb12719d7_3ad
In 2017, the German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re-evaluated the maximum workplace concentration (MAK value) of N,N-dimethylacetamide [127-19-5]. If the MAK value of 5 ml N,N-dimethylacetamide/m3 (18 mg/m3) is not exceeded, prenatal toxic effects are not to be expected and Pregnancy Risk Group C was confirmed. In 2019, the biological tolerance value (BAT value) of 25 mg N-methylacetamide plus N-hydroxymethyl-N-methylacetamide/l urine was derived in correlation to the MAK value. Therefore, Pregnancy Risk Group C is also valid for the BAT value. Adhering to the BAT value of 25 mg N-methylacetamide plus N-hydroxymethyl-N-methylacetamide/l urine, prenatal toxic effects are not to be expected.