Cyclosporin A modulates cellular localization of MEF2C protein and blocks fiber hypertrophy in the overloaded soleus muscle of mice

2008/03/27 by Kunihiro Sakuma, Mai Akiho, Hiroyuki Nakashima +5 · 6 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · Medicine · #Biochemistry #Biology #Cell biology #Chemistry #Endocrinology #Exercise and Physiological Responses #Gene expression #Internal medicine #MEF2C #Medicine #Muscle Physiology and Disorders #Muscle activation and electromyography studies #Muscle hypertrophy #MyoD #Myocyte #Myogenesis #Myogenin #Myosin #Sarcolemma #Skeletal muscle #Soleus muscle

paper · doi:10.1007/s00401-008-0371-5

openalex publication_date 2008/03/27 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/25

Citations

• Calcineurin is a potent regulator for skeletal muscle regeneration by association with NFATc1 and GATA-2
• Cyclosporin A treatment upregulates Id1 and Smad3 expression and delays skeletal muscle regeneration

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