Christopher S. Chen

1. Mechanical regulation of glycolysis via cytoskeleton architecture
   2020/02/12 by Jin Suk Park, Christoph J. Burckhardt, Rossana Lazcano +9 · 1 voice · 12 citations
   Biochemistry, Genetics and Molecular Biology · #Cellular Mechanics and Interactions #Endoplasmic Reticulum Stress and Disease #Heat shock proteins research
2. Geometric Control of Cell Life and Death
   1997/05/30 by Christopher S. Chen, Milan Mrksich, Sui Huang +2 · 3 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · Chemistry · #Cellular Mechanics and Interactions #Cell Adhesion Molecules Research #Cancer Cells and Metastasis #Extracellular matrix #Cell biology #Matrix (chemical analysis) #Adhesion #Integrin #Cell adhesion #Cell #Focal adhesion #Programmed cell death #Cell growth #Chemistry #Biology #Apoptosis #Biophysics #Signal transduction #Biochemistry
3. MicroBundleCompute: Automated segmentation, tracking, and analysis of subdomain deformation in cardiac microbundles
   2023/08/08 by Hiba Kobeissi, Kobeissi, Hiba, Javiera Jilberto +21 · 1 citation
   Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · #3D Printing in Biomedical Research #74A05 #92F05 #FOS: Biological sciences #J.2 #J.3 #Pluripotent Stem Cells Research #Quantitative Methods (q-bio.QM) #Tissue Engineering and Regenerative Medicine
4. Deconstructing the third dimension – how 3D culture microenvironments alter cellular cues
   2012/01/01 by Brendon M. Baker, Christopher S. Chen · 1 citation
   Biochemistry, Genetics and Molecular Biology · Engineering · Neuroscience · #Cellular Mechanics and Interactions #3D Printing in Biomedical Research #Bone Tissue Engineering Materials #Biology #Context (archaeology) #Mechanotransduction #Function (biology) #3D cell culture #Cell biology #Neuroscience #Cognitive science #Cell culture #Genetics
5. Emergence of Patterned Stem Cell Differentiation Within Multicellular Structures
   2008/08/14 by Sami Alom Ruiz, Christopher S. Chen · 1 citation
   Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · #Cellular Mechanics and Interactions #3D Printing in Biomedical Research #Cancer Cells and Metastasis #Multicellular organism #Biology #Cell biology #Stem cell #Cellular differentiation #Adipogenesis #Morphogenesis #Mesenchymal stem cell #Cell #Genetics #Gene
6. Matrix degradability controls multicellularity of 3D cell migration
   2017/08/23 by Britta Trappmann, Brendon M. Baker, William J. Polacheck +3 · 1 citation
   Engineering · Biochemistry, Genetics and Molecular Biology · Chemistry · #3D Printing in Biomedical Research #Cellular Mechanics and Interactions #Angiogenesis and VEGF in Cancer #Self-healing hydrogels #Microfluidics #Angiogenesis #Multicellular organism #Materials science #Matrix (chemical analysis) #Tissue engineering #Nanotechnology #Cell migration #Extracellular matrix #Cell #Biophysics #Cell biology #Biomedical engineering #Chemistry #Biology #Composite material
7. Engineering biomaterials to control cell function
   2005/11/19 by Wendy F. Liu, Christopher S. Chen · 1 citation
   Biochemistry, Genetics and Molecular Biology · Engineering · Materials Science · #Cellular Mechanics and Interactions #3D Printing in Biomedical Research #Silk-based biomaterials and applications #Cell function #Function (biology) #Tissue engineering #Nanotechnology #Biochemical engineering #Cell biology #Cell #Biology #Engineering #Materials science #Biomedical engineering
8. Mechanical tugging force regulates the size of cell–cell junctions
   2010/05/12 by Zhijun Liu, John L. Tan, Daniel M. Cohen +5 · 1 citation
   Biochemistry, Genetics and Molecular Biology · Medicine · Engineering · Chemistry · #Cellular Mechanics and Interactions #Cell Adhesion Molecules Research #3D Printing in Biomedical Research #Adherens junction #Myosin #Cell biology #Mechanotransduction #Focal adhesion #Cell #Cell adhesion #Rac GTP-Binding Proteins #Biophysics #Chemistry #RAC1 #Biology #Cadherin #Signal transduction #Biochemistry
9. HeLiVa platform: integrated heart-liver-vascular systems for drug testing in human health and disease
   2013/12/01 by Gordana Vunjak‐Novakovic, Sangeeta N. Bhatia, Christopher S. Chen +1 · 1 citation
   Engineering · Biochemistry, Genetics and Molecular Biology · Medicine · #3D Printing in Biomedical Research #Pluripotent Stem Cells Research #Biomedical and Engineering Education #Induced pluripotent stem cell #Human liver #Stem cell #Human heart #Computational biology #Drug discovery #Human Induced Pluripotent Stem Cells #Medicine #Biology #Bioinformatics #Embryonic stem cell #Cell biology #In vitro #Internal medicine #Genetics
10. 3D culture models of tissues under tension
    2016/01/01 by Jeroen Eyckmans, Christopher S. Chen · 1 citation
    Engineering · Biochemistry, Genetics and Molecular Biology · Medicine · #3D Printing in Biomedical Research #Cellular Mechanics and Interactions #Cancer Cells and Metastasis #Biology #Reciprocity (cultural anthropology) #Extracellular matrix #Function (biology) #Cell biology #Organoid #Cell function #Computational biology #Cell #Genetics
11. Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro
    2013/04/08 by Duc-Huy T. Nguyen, Sarah C. Stapleton, Michael T. Yang +4 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Engineering · Chemistry · #Angiogenesis and VEGF in Cancer #Cellular Mechanics and Interactions #3D Printing in Biomedical Research #Filopodia #Angiogenesis #Cell biology #Sprouting angiogenesis #Morphogenesis #Extracellular matrix #Neovascularization #Biology #Chemistry #Biochemistry #Cancer research #Actin
12. A DNA-based molecular probe for optically reporting cellular traction forces
    2014/10/12 by Brandon L Blakely, Brandon L. Blakely, Christoph E Dumelin +17 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Chemistry · Materials Science · Physics and Astronomy · #Biochemistry #Biology #Biophysics #Cellular Mechanics and Interactions #Chemistry #Composite material #Conjugated system #DNA #Fluorescence #Fluorophore #Force Microscopy Techniques and Applications #Materials science #Nanotechnology #Optics #Physics #Polymer #Polymer Surface Interaction Studies #Tension (geology) #Traction (geology) #Tractive force
13. Forces and mechanotransduction in 3D vascular biology
    2016/05/20 by Matthew L Kutys, Matthew L. Kutys, Christopher S. Chen +1 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · Neuroscience · #3D Printing in Biomedical Research #Biology #Cancer Cells and Metastasis #Cell biology #Cellular Mechanics and Interactions #Function (biology) #Genetics #Homeostasis #In vitro #In vivo #Mechanotransduction #Neuroscience
14. Geometric control of vascular networks to enhance engineered tissue integration and function
    2013/04/22 by Jan D. Baranski, Ritika Chaturvedi, Kelly R. Stevens +7 · 1 citation
    Engineering · Medicine · #3D Printing in Biomedical Research #Liver physiology and pathology #Tissue Engineering and Regenerative Medicine #Mural cell #Transplantation #Tissue engineering #Cell biology #Biology #Function (biology) #Translation (biology) #Actin #In vivo #Phenotype #Angiogenesis #Pathology #Anatomy #Vascular smooth muscle #Smooth muscle #Medicine #Cancer research #Messenger RNA #Internal medicine #Endocrinology #Gene #Biochemistry
15. A biomimetic pancreatic cancer on-chip reveals endothelial ablation via ALK7 signaling
    2019/08/02 by Duc-Huy T. Nguyen, Esak Lee, Styliani Alimperti +6 · 1 citation
    Engineering · Medicine · #3D Printing in Biomedical Research #Cancer Cells and Metastasis #Pancreatic and Hepatic Oncology Research #Pancreatic cancer #Signal transduction #Ablation #Cancer research #Cancer #Biology #Bioinformatics #Computational biology #Cell biology #Medicine #Internal medicine