Henne Holstege
- Alzheimer's disease
2021/03/02 by Philip Scheltens, Bart De Strooper, Miia Kivipelto +5 · 48 citations
Medicine · Neuroscience · #Alzheimer's disease research and treatments #Dementia and Cognitive Impairment Research #Neurological Disease Mechanisms and Treatments
- Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes
2023/08/29 by Yann Le Guen, Guo Luo, Aditya Ambati +97 · 1 voice · 1 citation
Immunology and Microbiology · Neuroscience · #Atherosclerosis and Cardiovascular Diseases #Neuroinflammation and Neurodegeneration Mechanisms #Tryptophan and brain disorders
- Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis
2014/04/23 by Henne Holstege, Wayne Pfeiffer, Daoud Sie +15 · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Cancer Genomics and Diagnostics #Acute Myeloid Leukemia Research #Genomics and Rare Diseases #Biology #Somatic cell #Haematopoiesis #Telomere #Genetics #Mutation #Germline mutation #Stem cell #Blood cell #Compartment (ship) #Genome #Gene #White (mutation) #Allele #Hematopoietic stem cell
- Machine learning in Alzheimer’s disease genetics
2025/07/21 by Matthew Bracher‐Smith, Federico Melograna, Brittany Ulm +97 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · #Bioinformatics and Genomic Networks #Gene expression and cancer classification #Genetic Associations and Epidemiology