Yann Le Guen

1. Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes
   2023/08/29 by Yann Le Guen, Guo Luo, Aditya Ambati +97 · 1 voice · 1 citation
   Immunology and Microbiology · Neuroscience · #Atherosclerosis and Cardiovascular Diseases #Neuroinflammation and Neurodegeneration Mechanisms #Tryptophan and brain disorders
2. Deep neural networks with controlled variable selection for the identification of putative causal genetic variants
   2021/09/29 by Peyman Hosseinzadeh Kassani, Kassani, Peyman H., Fred Lu +5 · 1 citation
   Biochemistry, Genetics and Molecular Biology · #Gene expression and cancer classification #Machine Learning in Bioinformatics #Genetic Associations and Epidemiology
3. Plasma proteomics links brain and immune system aging with healthspan and longevity
   2025/07/09 by Hamilton Oh, Yann Le Guen, Nimrod Rappoport +9 · 2 voices · 2 citations
   Neuroscience · Biochemistry, Genetics and Molecular Biology · #Neuroinflammation and Neurodegeneration Mechanisms #Tryptophan and brain disorders #Genetics, Aging, and Longevity in Model Organisms