David Botstein
- Gene Ontology: tool for the unification of biology
2000/05/01 by Michael Ashburner, Catherine A. Ball, Judith A. Blake +20 · 399 citations
Biochemistry, Genetics and Molecular Biology · #Bioinformatics and Genomic Networks #Biomedical Text Mining and Ontologies #Microbial Metabolic Engineering and Bioproduction
- Comprehensive Identification of Cell Cycle–regulated Genes of the YeastSaccharomyces cerevisiaeby Microarray Hybridization
1998/12/01 by Paul T. Spellman, Gavin Sherlock, Michael Q. Zhang +6 · 22 citations
Biochemistry, Genetics and Molecular Biology · #Biology #Cell biology #Cell cycle #Computational biology #Cyclin #Cyclin A #Cyclin-dependent kinase 1 #DNA microarray #Fungal and yeast genetics research #Gene #Gene expression #Gene expression and cancer classification #Genetics #Genomics and Chromatin Dynamics #Saccharomyces cerevisiae
- Singular value decomposition for genome-wide expression data processing and modeling
2000/08/29 by Orly Alter, Patrick O. Brown, David Botstein · 9 citations
Biochemistry, Genetics and Molecular Biology · #Gene expression and cancer classification #Gene Regulatory Network Analysis #Genomics and Chromatin Dynamics #Normalization (sociology) #Genome #Computational biology #Singular value decomposition #Biology #Gene #Sorting #Expression (computer science) #Orthonormal basis #Genetics #Algorithm #Computer science #Physics
- Genomic Expression Programs in the Response of Yeast Cells to Environmental Changes
2000/12/01 by Audrey P. Gasch, Paul T. Spellman, Camilla M. Kao +5 · 6 citations
- Dietary restriction impacts health and lifespan of genetically diverse mice
2024/10/09 by Andrea Di Francesco, Andrew Deighan, Lev Litichevskiy +20 · 1 voice · 7 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Birth, Development, and Health #Dietary Effects on Health #Genetics, Aging, and Longevity in Model Organisms
- Evaluating Gene Expression Dynamics Using Pairwise RNA FISH Data
2010/11/04 by Matthieu Wyart, David Botstein, Ned S. Wingreen · 1 citation
Biochemistry, Genetics and Molecular Biology · #Algorithm #Artificial intelligence #Biological system #Biology #Computational biology #Computer science #Database #Gene #Gene Regulatory Network Analysis #Gene expression #Gene expression profiling #Genetics #Microbial Metabolic Engineering and Bioproduction #Pairwise comparison #RNA #Single-cell and spatial transcriptomics #Snapshot (computer storage) #Thresholding
- A Polymorphism in the β1 Adrenergic Receptor Is Associated with Resting Heart Rate
2002/04/01 by Koustubh Ranade, Eric Jorgenson, Wayne Huey‐Herng Sheu +15 · 1 citation
Medicine · #Cardiac electrophysiology and arrhythmias #Heart Rate Variability and Autonomic Control #Heart rate and cardiovascular health