Nicholas Kelley
- Simulating oligomerization at experimental concentrations and long timescales: A Markov state model approach
2008/12/04 by Nicholas Kelley, V. Vishal, Grant A. Krafft +1 · 5 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Computer Science · Chemistry · #Protein Structure and Dynamics #Alzheimer's disease research and treatments #Computational Drug Discovery Methods #Oligomer #Molecular dynamics #Markov chain #Chemistry #Statistical physics #Biological system #Computer science #Computational chemistry #Algorithm #Physics #Biology #Machine learning
- Rationally Designed Turn Promoting Mutation in the Amyloid-β Peptide Sequence Stabilizes Oligomers in Solution
2011/07/22 by Jayakumar Rajadas, Corey W. Liu, Paul Novick +4 · 2 citations
Medicine · Biochemistry, Genetics and Molecular Biology · Mathematics · Chemistry · #Alzheimer's disease research and treatments #Protein Structure and Dynamics #Graph theory and applications #Oligomer #Peptide #Fibril #Amyloid (mycology) #Biophysics #P3 peptide #Chemistry #Protein structure #Mutant #Amyloid beta #Turn (biochemistry) #Peptide sequence #Molecular dynamics #Biochemistry #Alzheimer's disease #Biology #Amyloid precursor protein #Medicine #Disease #Organic chemistry
- The Predicted Structure of the Headpiece of the Huntingtin Protein and Its Implications on Huntingtin Aggregation
2009/01/24 by Nicholas Kelley, Nicholas W. Kelley, Xuhui Huang +5 · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · Materials Science · Neuroscience · #Biochemistry #Biology #Biophysics #Chemical physics #Chemistry #Computational chemistry #Crystallography #Enzyme Structure and Function #Genetic Neurodegenerative Diseases #Helix (gastropod) #Huntingtin #Huntingtin Protein #Molecular dynamics #Mutant #Nucleation #Protein Structure and Dynamics #Protein folding #Protein secondary structure #Protein structure
- Motivations and outcomes of women’s pornography use
2026/07/22 by Katerina Litsou, Cynthia A. Graham, Cynthia Graham +3 · 1 voice
Psychology · Social Sciences · #Affect (linguistics) #Impact of Technology on Adolescents #Perception #Perspective (graphical) #Pornography #Qualitative research #Sex work and related issues #Sexuality, Behavior, and Technology