Douglas C. Wallace

1. Natural selection shaped regional mtDNA variation in humans
   2002/12/30 by Dan Mishmar, Eduardo Ruiz‐Pesini, Paweł Golik +10 · 64 citations
   Biochemistry, Genetics and Molecular Biology · #Genomics and Phylogenetic Studies #Molecular Biology Techniques and Applications #Mitochondrial Function and Pathology #Nonsynonymous substitution #Mitochondrial DNA #Biology #Genetics #Natural selection #Gene #Negative selection #Genetic variation #Synonymous substitution #Cytochrome c oxidase #Cytochrome b #Evolutionary biology #Mitochondrion #Codon usage bias #Selection (genetic algorithm) #Genome
2. A Back Migration from Asia to Sub-Saharan Africa Is Supported by High-Resolution Analysis of Human Y-Chromosome Haplotypes
   2002/05/01 by Fulvio Cruciani, Piero Santolamazza, P. Santolamazza +15 · 24 citations
   Biochemistry, Genetics and Molecular Biology · #Allele #Analysis of molecular variance #Biology #Demography #Evolutionary biology #Forensic and Genetic Research #Gene #Genetic Associations and Epidemiology #Genetics #Geography #Haplogroup #Haplotype #Microsatellite #Out of africa #Phylogenetic tree #Phylogeography #Population #Race, Genetics, and Society #Y chromosome
3. mtDNA Variation in the South African Kung and Khwe—and Their Genetic Relationships to Other African Populations
   2000/04/01 by Yu-Sheng Chen, Yusheng Chen, Antonel Olckers +4 · 33 citations
   Arts and Humanities · Biochemistry, Genetics and Molecular Biology · #Forensic Anthropology and Bioarchaeology Studies #Forensic and Genetic Research #Genetic diversity and population structure
4. A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine
   2005/07/19 by Douglas C. Wallace · 54 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #Biochemistry #Biology #Cancer #Diet and metabolism studies #Disease #Gene #Genetics #Medicine #Metabolism and Genetic Disorders #Mitochondrial DNA #Mitochondrial Function and Pathology #Mitochondrion #Oxidative phosphorylation #Pathology #Somatic cell
5. Classification of European mtDNAs From an Analysis of Three European Populations
   1996/12/01 by Antonio Torroni, Kirsi Huoponen, Paolo Francalacci +6 · 19 citations
   Biochemistry, Genetics and Molecular Biology · #Forensic and Genetic Research #Genetic diversity and population structure #Genomics and Phylogenetic Studies #Haplogroup #Mitochondrial DNA #Biology #Genetics #Hypervariable region #Subclade #mtDNA control region #Human mitochondrial DNA haplogroup #Human mitochondrial genetics #Haplotype #Evolutionary biology #Sequence (biology) #Gene #Phylogenetics #Allele #Clade
6. Mitochondrial DNA variation in human evolution and disease
   1999/09/01 by Douglas C. Wallace, Michael D. Brown, Marie T. Lott · 16 citations
   Biochemistry, Genetics and Molecular Biology · #Metabolism and Genetic Disorders #Metabolomics and Mass Spectrometry Studies #Mitochondrial Function and Pathology
7. The Dual Origin and Siberian Affinities of Native American Y Chromosomes
   2002/01/01 by Jeffrey T. Lell, Rem I. Sukernik, R. I. Sukernik +7 · 11 citations
   Biochemistry, Genetics and Molecular Biology · #Affinities #Biochemistry #Biology #Dual (grammatical number) #Evolutionary biology #Forensic and Genetic Research #Genetic diversity and population structure #Genetics #Linguistics #Philosophy #Race, Genetics, and Society
8. Mitochondrial Genome Diversity in Arctic Siberians, with Particular Reference to the Evolutionary History of Beringia and Pleistocenic Peopling of the Americas
   2008/05/01 by Natalia V. Volodko, Natalia Volodko, Elena B. Starikovskaya +8 · 12 citations
   Arts and Humanities · Biochemistry, Genetics and Molecular Biology · #Ancient DNA #Arctic #Beringia #Biology #Demography #Ecology #Evolutionary biology #Forensic Anthropology and Bioarchaeology Studies #Forensic and Genetic Research #Genetic diversity #Genetics #Geography #Haplogroup #Haplotype #Human mitochondrial DNA haplogroup #Lineage (genetic) #Mitochondrial DNA #Paleontology #Pleistocene #Population #Yersinia bacterium, plague, ectoparasites research
9. mtDNA Haplogroup X: An Ancient Link between Europe/Western Asia and North America?
   1998/12/01 by Michael D. Brown, Seyed H. Hosseini, Antonio Torroni +7 · 22 citations
   Biochemistry, Genetics and Molecular Biology · #Forensic and Genetic Research #Genetic diversity and population structure #Genomics and Phylogenetic Studies
10. The structure of human mitochondrial DNA variation
    1991/12/01 by D. Andrew Merriwether, Andrew G. Clark, Scott W. Ballinger +5 · 37 citations
    Biochemistry, Genetics and Molecular Biology · #Allele #Balancing selection #Biology #Evolutionary biology #Gene #Genetic diversity #Genetic variation #Genetics #Genome #Haplogroup #Haplotype #Linkage disequilibrium #Metabolism and Genetic Disorders #Metabolomics and Mass Spectrometry Studies #Mitochondrial DNA #Mitochondrial Function and Pathology #Negative selection #Neutral theory of molecular evolution #Nucleotide diversity #Population #Population genetics #Selective sweep
11. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
    1995/12/01 by Yibing Li, Ting-Ting Huang, Ting‐Ting Huang +12 · 21 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Cardiac Ischemia and Reperfusion #Coenzyme Q10 studies and effects #Mitochondrial Function and Pathology
12. Incapaces de desconectar: La adición al trabajo puede convertirse en uno de los problemas laborales más graves de este siglo
    2002/08/01 by Olga Derbeneva, R. I. Sukernik, Natalia Volodko +4 · 15 citations
    Arts and Humanities · Biochemistry, Genetics and Molecular Biology · Health Professions · Social Sciences · #Archaeology #Archipelago #Beringia #Biological dispersal #Biology #Demography #Employment, Labor, and Gender Studies #Evolutionary biology #Forensic Anthropology and Bioarchaeology Studies #Forensic and Genetic Research #Genetics #Genotype #Geography #Haplogroup #Haplotype #Humanities #Indigenous Studies and Ecology #Labor Law and Work Dynamics #Land bridge #Lineage (genetic) #Mitochondrial DNA #Philosophy #Population #Social Sciences and Policies
13. Mitochondrial DNA Diversity in Indigenous Populations of the Southern Extent of Siberia, and the Origins of Native American Haplogroups
    2005/01/01 by Elena B. Starikovskaya, R. I. Sukernik, Olga Derbeneva +8 · 6 citations
    Biochemistry, Genetics and Molecular Biology · Arts and Humanities · #Forensic and Genetic Research #Forensic Anthropology and Bioarchaeology Studies #Yersinia bacterium, plague, ectoparasites research #Haplogroup #Mitochondrial DNA #Biology #Haplotype #Phylogenetic tree #Lineage (genetic) #Human mitochondrial DNA haplogroup #Hypervariable region #Gene pool #Evolutionary biology #Genetic diversity #Genetics #Population #Gene #Allele #Demography
14. Trans-mitochondrial coordination of cristae at regulated membrane junctions
    2015/02/17 by Martin Picard, Meagan J. McManus, György Csordás +5 · 1 voice · 7 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · #ATP Synthase and ATPases Research #Bioenergetics #Biology #Biophysics #Cell biology #Chemistry #Coupling (piping) #Endomembrane system #Endoplasmic reticulum #Intracellular #Materials science #Mitochondrial Function and Pathology #Mitochondrion #Organelle #RNA and protein synthesis mechanisms
15. Pancreatitis aguda recurrente
    1992/01/01 by Scott W. Ballinger, Theodore G. Schurr, Antonio Torroni +10 · 3 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #DNA #Demography #Evolutionary biology #Gene #Genetics #Genomics and Phylogenetic Studies #Human genetics #Internal medicine #Medicine #Metabolomics and Mass Spectrometry Studies #Mitochondrial DNA #Mitochondrial Function and Pathology #Mongoloid #Pancreatitis #Pancreatitis Pathology and Treatment
16. Mitochondrial DNA variant associated with Leber hereditary optic neuropathy and high-altitude Tibetans
    2012/04/18 by Fuyun Ji, Mark S. Sharpley, Olga Derbeneva +18 · 3 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Mitochondrial Function and Pathology #Metabolomics and Mass Spectrometry Studies #Metabolism and Genetic Disorders #Haplogroup #Human mitochondrial DNA haplogroup #Genetics #Leber's hereditary optic neuropathy #Mitochondrial DNA #Biology #Context (archaeology) #Human mitochondrial genetics #Allele #Odds ratio #Haplotype #Gene #Medicine #Internal medicine
17. Lethal COVID-19 associates with RAAS-induced inflammation for multiple organ damage including mediastinal lymph nodes
    2024/11/27 by Michael J. Topper, Joseph W. Guarnieri, Jeffrey Haltom +57 · 2 voices · 7 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Biology #COVID-19 Clinical Research Studies #Cancer #Coronavirus disease 2019 (COVID-19) #Cytokine storm #Dermatological and COVID-19 studies #Immune system #Immunology #Inflammasome and immune disorders #Inflammation #Internal medicine #Lung #Lymph #Lymph node #Mediastinal lymph node #Medicine #Pathology
18. Mitochondrial DNA in anucleate human blood cells
    1988/09/01 by Robert C. Shuster, Andrew J. Rubenstein, Douglas C. Wallace · 2 citations
    Biochemistry, Genetics and Molecular Biology · Chemistry · #Biochemistry #Biology #Chemistry #DNA #Fluorescence #Gene #Immunology #Lysis #Metabolism and Genetic Disorders #Metabolomics and Mass Spectrometry Studies #Mitochondrial DNA #Mitochondrial Function and Pathology #Mitochondrion #Molecular biology #Platelet #Rhodamine #Rhodamine 123
19. American Indian Prehistory as Written in the Mitochondrial DNA: A Review
    2009/12/01 by Douglas C. Wallace, Antonio Torroni · 2 citations
    Biochemistry, Genetics and Molecular Biology · #Forensic and Genetic Research #Genomics and Phylogenetic Studies #Molecular Biology Techniques and Applications #Lineage (genetic) #Mitochondrial DNA #Prehistory #Evolutionary biology #Genetic variation #Biology #Genetics #Geography #Gene #Paleontology
20. Highly efficient 5' capping of mitochondrial RNA with NAD+ and NADH by yeast and human mitochondrial RNA polymerase
    2018/12/10 by Jeremy G. Bird, Urmimala Basu, David Kuster +9 · 2 citations
    Biochemistry, Genetics and Molecular Biology · #RNA and protein synthesis mechanisms #RNA modifications and cancer #RNA Research and Splicing
21. MITOMASTER: a bioinformatics tool for the analysis of mitochondrial DNA sequences
    2008/06/19 by Marty C. Brandon, Eduardo Ruiz‐Pesini, Eduardo Ruiz-Pesini +8 · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Metabolism and Genetic Disorders #Metabolomics and Mass Spectrometry Studies #Mitochondrial Function and Pathology
22. Cytoplasmic transfer of chloramphenicol resistance in human tissue culture cells.
    1975/10/01 by D C Wallace, Douglas C. Wallace, C L Bunn +3 · 23 citations
    Biochemistry, Genetics and Molecular Biology · #Antibiotics #Biology #Cancer therapeutics and mechanisms #Cell culture #Cell fusion #Chloramphenicol #Cytoplasm #DNA Repair Mechanisms #Genetics #HeLa #In vitro #Molecular Biology Techniques and Applications #Molecular biology #Tissue culture
23. Evaluation of the stiffness modulus of bituminous mixtures using laboratory tests (NAT) validate by field back-analysis
    1998/02/01 by Simon Melov, Julie A. Schneider, Brian J. Day +7 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · #Alzheimer's disease research and treatments #Amyotrophic Lateral Sclerosis Research #Asphalt Pavement Performance Evaluation #Infrastructure Maintenance and Monitoring #Mitochondrial Function and Pathology #Transport Systems and Technology
24. Mitochondrial DNA haplogroups influence AIDS progression
    2008/11/13 by Sher L. Hendrickson, Holli B. Hutcheson, Eduardo Ruiz‐Pesini +9 · 1 citation
    Medicine · Immunology and Microbiology · Biochemistry, Genetics and Molecular Biology · #HIV-related health complications and treatments #HIV Research and Treatment #Mitochondrial Function and Pathology
25. Ancient mtDNA Genetic Variants Modulate mtDNA Transcription and Replication
    2009/05/07 by Sarit Suissa, Zhibo Wang, Jason C. Poole +6 · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Mitochondrial Function and Pathology #Metabolism and Genetic Disorders #Metabolomics and Mass Spectrometry Studies #Haplogroup #Biology #Human mitochondrial DNA haplogroup #Genetics #Mitochondrial DNA #Haplotype #Gene #Allele
26. Respiratory viral infections awaken metastatic breast cancer cells in lungs
    2025/07/30 by Shi B. Chia, Bryan Johnson, Junxiao Hu +26 · 1 voice · 2 citations
    Medicine · #Cancer Cells and Metastasis #Cancer Immunotherapy and Biomarkers #Lung Cancer Diagnosis and Treatment