Hans Clevers
- A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity
2017/12/07 by Norman Sachs, Joep de Ligt, Oded Kopper +38 · 1 voice · 19 citations
Medicine · Biochemistry, Genetics and Molecular Biology · #Cancer Cells and Metastasis #Cancer Genomics and Diagnostics #Cancer Immunotherapy and Biomarkers
- Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
2005/06/01 by Johan H. van Es, Mariëlle van Gijn, Marielle E. van Gijn +9 · 30 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Hedgehog Signaling Pathway Studies #Cancer Cells and Metastasis #Wnt/β-catenin signaling in development and cancer
- The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength
2014/02/14 by Wim de Lau, Weng Chuan Peng, Piet Gros +1 · 3 citations
- A turquoise fluorescence lifetime-based biosensor for quantitative imaging of intracellular calcium
2021/12/09 by Franka H. van der Linden, Eike K. Mahlandt, Janine Arts +10 · 1 voice · 4 citations
Biochemistry, Genetics and Molecular Biology · #Advanced Fluorescence Microscopy Techniques #Advanced biosensing and bioanalysis techniques #bioluminescence and chemiluminescence research
- Organoid cultures for the analysis of cancer phenotypes
2014/01/03 by Norman Sachs, Hans Clevers · 2 citations
Medicine · Engineering · Biochemistry, Genetics and Molecular Biology · #Cancer Cells and Metastasis #3D Printing in Biomedical Research #Cancer Genomics and Diagnostics
- Translational applications of adult stem cell-derived organoids
2017/03/15 by Jarno Drost, Hans Clevers · 1 citation
- Human gut M cells resemble dendritic cells and present gluten antigen
2025/12/10 by Daisong Wang, Sangho Lim, Willine J. van de Wetering +19 · 1 voice · 5 citations
Medicine · #Celiac Disease Research and Management #Microscopic Colitis #Gastrointestinal motility and disorders
- Protocol for the generation and differentiation of thymic epithelial organoids from adult mouse thymus tissue
2025/06/01 by Sam Willemsen, Ni Luh Wisma Eka Yanti, Johan H. van Es +2 · 1 voice · 1 citation
Medicine · #Childhood Cancer Survivors' Quality of Life #Myasthenia Gravis and Thymoma #Lymphatic System and Diseases
- A human organoid model of alveolar regeneration reveals distinct epithelial responses to interferon-gamma
2025/01/31 by Antonella F. M. Dost, Katarína Balážová, Carla Pou Casellas +10 · 1 voice · 1 citation
Medicine · #Medical Imaging and Pathology Studies #Neonatal Respiratory Health Research #Respiratory viral infections research
- Epithelial tension controls intestinal cell extrusion
2025/09/04 by Daniel Krueger, Willem Kasper Spoelstra, Dirk Jan Mastebroek +10 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · #3D Printing in Biomedical Research #Cancer Cells and Metastasis #Cellular Mechanics and Interactions