Philip L. De Jager
- Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores
2015/10/01 by Bjarni J. Vilhjálmsson, Bjarni J. Vilhjálmsson, Jian Yang +438 · 56 citations
Biochemistry, Genetics and Molecular Biology · Mathematics · #Genetic Associations and Epidemiology #Bioinformatics and Genomic Networks #Advanced Causal Inference Techniques
- Microglia states and nomenclature: A field at its crossroads
2022/11/01 by Rosa C. Paolicelli, Rosa Chiara Paolicelli, Amanda Sierra +118 · 33 citations
Immunology and Microbiology · Medicine · Neuroscience · #Chemokine receptors and signaling #Immune cells in cancer #Neuroinflammation and Neurodegeneration Mechanisms
- Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease
2020/11/30 by Marta Olah, Vilas Menon, Naomi Habib +24 · 16 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Neuroscience · #Immune cells in cancer #Neuroinflammation and Neurodegeneration Mechanisms #Single-cell and spatial transcriptomics
- Parsing the Interferon Transcriptional Network and Its Disease Associations
2016/01/01 by Sara Mostafavi, Hideyuki Yoshida, Devapregasan Moodley +26 · 8 citations
Immunology and Microbiology · Biochemistry, Genetics and Molecular Biology · Medicine · #interferon and immune responses #RNA and protein synthesis mechanisms #Cytokine Signaling Pathways and Interactions
- A human brain map of mitochondrial respiratory capacity and diversity
2025/03/26 by Eugene V. Mosharov, Ayelet M Rosenberg, Ayelet M. Rosenberg +23 · 3 voices · 31 citations
Biochemistry, Genetics and Molecular Biology · Neuroscience · Medicine · #Mitochondrial Function and Pathology #Neuroscience of respiration and sleep #Diet and metabolism studies
- Genetics of rheumatoid arthritis contributes to biology and drug discovery
2013/12/24 by Yukinori Okada, Di Wu, Gosia Trynka +111 · 3 citations
Medicine · #Chronic Lymphocytic Leukemia Research #Cytokine Signaling Pathways and Interactions #Monoclonal and Polyclonal Antibodies Research
- APOE and cerebral amyloid angiopathy in community-dwelling older persons
2015/08/15 by Lei Yu, Patricia A. Boyle, Sukriti Nag +10 · 1 citation
Medicine · #Alzheimer's disease research and treatments #Intracerebral and Subarachnoid Hemorrhage Research #Dementia and Cognitive Impairment Research
- A cross-disease resource of living human microglia identifies disease-enriched subsets and tool compounds recapitulating microglial states
2024/10/15 by John F. Tuddenham, Mariko Taga, Verena Haage +38 · 1 voice · 1 citation
Immunology and Microbiology · Neuroscience · #Atherosclerosis and Cardiovascular Diseases #Immune cells in cancer #Neuroinflammation and Neurodegeneration Mechanisms
- A common polymorphism near PER1 and the timing of human behavioral rhythms
2012/04/26 by Andrew Lim, Anne‐Marie Chang, Joshua Shulman +12 · 1 citation
Neuroscience · Psychology · #Circadian rhythm and melatonin #Sleep and Wakefulness Research #Sleep and related disorders
- Parkinson's Disease: Genetics and Pathogenesis
2011/01/24 by Joshua Shulman, Philip L. De Jager, Mel Β. Feany · 1 citation
Medicine · Neuroscience · #Parkinson's Disease Mechanisms and Treatments #Nuclear Receptors and Signaling #Neurological diseases and metabolism