Kathleen M. Giacomini

1. The full spectrum of SLC22 OCT1 mutations illuminates the bridge between drug transporter biophysics and pharmacogenomics
   2024/05/01 by Sook Wah Yee, Christian B. Macdonald, Darko Mitrovic +14 · 1 voice · 22 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #Amino Acid Enzymes and Metabolism #Biology #Computational biology #Drug Transport and Resistance Mechanisms #Functional genomics #Gene #Genetics #Genome #Genomics #HIV/AIDS drug development and treatment #Missense mutation #Mutagenesis #Mutant #Mutation #Organic cation transport proteins #Pharmacogenomics #Phenotype #Saturated mutagenesis #Solute carrier family #Transporter
2. Drug Metabolites Potently Inhibit Renal Organic Anion Transporters, OAT1 and OAT3
   2020/09/07 by Ling Zou, Pär Matsson, Adrian Stecula +5 · 11 citations
   Chemistry · Medicine · #Biochemistry #Biology #Chemistry #Drug #Drug Transport and Resistance Mechanisms #Drug metabolism #HIV/AIDS drug development and treatment #Metabolite #Organic anion transporter 1 #Pharmacological Effects and Toxicity Studies #Pharmacology #Transporter