Kresten Lindorff-Larsen
- Experimental Parameterization of an Energy Function for the Simulation of Unfolded Proteins
2007/09/07 by Anders B. Norgaard, Jesper Ferkinghoff‐Borg, Jesper Ferkinghoff-Borg +2 · 1 voice · 17 citations
Biochemistry, Genetics and Molecular Biology · Materials Science · #Protein Structure and Dynamics #Enzyme Structure and Function #RNA and protein synthesis mechanisms
- Simultaneous determination of protein structure and dynamics
2005/01/13 by Kresten Lindorff‐Larsen, Kresten Lindorff-Larsen, Robert B. Best +3 · 1 voice · 17 citations
Materials Science · Biochemistry, Genetics and Molecular Biology · #Enzyme Structure and Function #Protein Structure and Dynamics #Photosynthetic Processes and Mechanisms
- Conformational ensembles of the human intrinsically disordered proteome
2024/01/31 by Giulio Tesei, Anna Ida Trolle, Nicolas Jonsson +6 · 1 voice · 19 citations
Biochemistry, Genetics and Molecular Biology · #Machine Learning in Bioinformatics #RNA and protein synthesis mechanisms #RNA modifications and cancer
- Software package for simulations using the coarse-grained CALVADOS model
2025/04/14 by Sören von Bülow, von Bülow, Sören, Ikki Yasuda +17 · 3 voices · 4 citations
Decision Sciences · #Simulation Techniques and Applications
- Computational design of intrinsically disordered proteins
2025/09/15 by Giulio Tesei, Francesco Pesce, Tesei, Giulio +4 · 4 voices · 2 citations
Biochemistry, Genetics and Molecular Biology · Materials Science · #Protein Structure and Dynamics #q-bio.BM
- Machine learning methods to study sequence-ensemble-function relationships in disordered proteins
2024/10/21 by Sören von Bülow, Giulio Tesei, von Bülow, Sören +4 · 1 voice · 4 citations
Biochemistry, Genetics and Molecular Biology · #Protein Structure and Dynamics #Machine Learning in Bioinformatics
- Transition states for protein folding have native topologies despite high structural variability
2004/04/18 by Kresten Lindorff‐Larsen, Kresten Lindorff-Larsen, Michele Vendruscolo +3 · 1 voice · 2 citations
Biochemistry, Genetics and Molecular Biology · Materials Science · #Enzyme Structure and Function #Protein Structure and Dynamics #RNA and protein synthesis mechanisms
- Disease-linked mutations cause exposure of a protein quality control degron
2022/06/13 by Caroline Kampmeyer, Sven Larsen-Ledet, Morten Rose Wagnkilde +14 · 3 citations
Biochemistry, Genetics and Molecular Biology · #Endoplasmic Reticulum Stress and Disease #Heat shock proteins research #Ubiquitin and proteasome pathways
- The mechanism of amyloid fibril growth from Φ-value analysis
2025/01/16 by Jacob Aunstrup Larsen, Abigail Barclay, Nicola Vettore +7 · 1 voice · 2 citations
Medicine · Biochemistry, Genetics and Molecular Biology · Materials Science · #Alzheimer's disease research and treatments #Protein Structure and Dynamics #Enzyme Structure and Function
- Computational Redesign of Thioredoxin Is Hypersensitive toward Minor Conformational Changes in the Backbone Template
2016/09/20 by Kristoffer E. Johansson, Nicolai Tidemand Johansen, Signe Christensen +10 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · Materials Science · #Enzyme Structure and Function #Protein Structure and Dynamics #RNA and protein synthesis mechanisms
- Zero-shot protein stability prediction by inverse folding models: a free energy interpretation
2025/06/05 by Jes Frellsen, Frellsen, Jes, Maher M. Kassem +11 · 2 voices · 2 citations
#cs.LG #cs.AI #q-bio.BM #stat.ML
- How to Use Quantum Computers for Biomolecular Free Energies
2025/06/25 by Jakob Günther, Thomas Weymuth, Günther, Jakob +44 · 2 voices · 2 citations
Computer Science · #Quantum Computing Algorithms and Architecture
- A near-complete map of human cytosolic degrons and their relevance for disease
2026/02/06 by Vasileios Voutsinos, Kristoffer E. Johansson, Fia B. Larsen +8 · 1 voice · 5 citations
Biochemistry, Genetics and Molecular Biology · #Ubiquitin and proteasome pathways #Protein Degradation and Inhibitors #Cell death mechanisms and regulation
- Towards a Unified Framework for Determining Conformational Ensembles of Disordered Proteins
2025/04/04 by Hamidreza Ghafouri, Pavel Kadeřávek, Ghafouri, Hamidreza +58 · 2 voices · 1 citation
Biochemistry, Genetics and Molecular Biology · Computer Science · #Bioinformatics and Genomic Networks #Computational Drug Discovery Methods #Protein Structure and Dynamics #q-bio.BM #q-bio.QM
- Detection of residual native state entropy changes upon mutation in Fyn SH3
2026/05/14 by Kresten Lindorff-Larsen, Robert B. Best, Anthony Mittermaier +3 · 3 voices
#q-bio.BM
- Disagreement among variant effect predictors guides experimental prioritization of target proteins
2026/03/20 by Nicolas Jonsson, Joseph A Marsh, Kresten Lindorff-Larsen · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · #Genomics and Rare Diseases #Genetic Associations and Epidemiology #Genomics and Phylogenetic Studies
- Comprehensive Variant Effect Map of Parkin-Mediated Mitophagy in Parkinson’s Disease
2026/02/09 by Erna Sól Sigmarsdóttir, Vasileios Voutsinos, Kristoffer E. Johansson +4 · 1 voice · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · #Autophagy in Disease and Therapy #Parkinson's Disease Mechanisms and Treatments #Ubiquitin and proteasome pathways
- Proteasomal control of transcription factors: mechanisms, regulation and dysregulation
2026/03/01 by Fia B. Larsen, Birthe B. Kragelund, Kresten Lindorff-Larsen +2 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · #Ubiquitin and proteasome pathways #Protein Degradation and Inhibitors #Endoplasmic Reticulum Stress and Disease