Nick Craddock
- Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores
2015/10/01 by Bjarni J. Vilhjálmsson, Bjarni J. Vilhjálmsson, Jian Yang +452 · 60 citations
Biochemistry, Genetics and Molecular Biology · Mathematics · Medicine · #Advanced Causal Inference Techniques #Allele #Artificial intelligence #Bioinformatics and Genomic Networks #Biology #Computer science #Disequilibrium #Genetic Associations and Epidemiology #Genetics #Haplotype #Linkage disequilibrium #Mathematics #Medicine #Pattern recognition (psychology) #Polygenic risk score #Pruning #Sample (material) #Sample size determination #Single-nucleotide polymorphism #Statistics #Thresholding
- Biological insights from 108 schizophrenia-associated genetic loci
2014/07/01 by Stephan Ripke, B M Neale, Kai-How Farh +97 · 17 citations
Biochemistry, Genetics and Molecular Biology · Neuroscience · #Diabetes and associated disorders #Genetic Associations and Epidemiology #Tryptophan and brain disorders
- Genome Scan Meta-Analysis of Schizophrenia and Bipolar Disorder, Part III: Bipolar Disorder
2003/07/01 by Ricardo Segurado, Sevilla D. Detera‐Wadleigh, Sevilla D. Detera-Wadleigh +87 · 4 citations
Biochemistry, Genetics and Molecular Biology · #Bioinformatics and Genomic Networks #Genetic Associations and Epidemiology #Genetic Mapping and Diversity in Plants and Animals
- Genetics of bipolar disorder
2013/05/01 by Nick Craddock, Pamela Sklar · 3 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Bipolar Disorder and Treatment #Genetic Associations and Epidemiology #Genetic Syndromes and Imprinting
- Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
2018/04/26 by eQTLGen, Naomi R. Wray, 23andMe +237 · 4 citations
Biochemistry, Genetics and Molecular Biology · #BRCA gene mutations in cancer #Genetic Associations and Epidemiology #Genetics and Neurodevelopmental Disorders
- Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies
2025/01/14 by Mark J. Adams, F Streit, Xiangrui Meng +97 · 2 voices · 6 citations
Biochemistry, Genetics and Molecular Biology · Neuroscience · Psychology · #Genetic Associations and Epidemiology #Mental Health Research Topics #Tryptophan and brain disorders
- The Kraepelinian dichotomy – going, going … but still not gone
2010/01/29 by Nick Craddock, Michael J. Owen · 2 citations
Biochemistry, Genetics and Molecular Biology · Psychology · #Genomics and Rare Diseases #Genomic variations and chromosomal abnormalities #Genetic Associations and Epidemiology #Schizophrenia (object-oriented programming) #Autism #Bipolar disorder #Psychology #Psychiatry #Cognition
- Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium
2017/09/22 by Wouter J. Peyrot, Sandra Van der Auwera, Pamela A. F. Madden +92 · 1 citation
Biochemistry, Genetics and Molecular Biology · Psychology · #Genetic Associations and Epidemiology #Cognitive Abilities and Testing #Child Abuse and Trauma
- The beginning of the end for the Kraepelinian dichotomy
2005/04/29 by Nick Craddock, Michael J. Owen · 1 citation
Biochemistry, Genetics and Molecular Biology · Mathematics · Medicine · Neuroscience · #Computer science #Content (measure theory) #Diet and metabolism studies #Genetic Neurodegenerative Diseases #Mathematics #Mitochondrial Function and Pathology