Alkes L. Price
- Reconstructing Indian population history
2009/09/01 by David Reich, Kumarasamy Thangaraj, Nick Patterson +2 · 87 citations
Biochemistry, Genetics and Molecular Biology · #Forensic and Genetic Research #Genetic diversity and population structure #Race, Genetics, and Society
- Reconstructing Native American population history
2012/07/10 by David Reich, Nick Patterson, Desmond Campbell +93 · 44 citations
Environmental Science · Health Professions · Social Sciences · #Indigenous Studies and Ecology #Pacific and Southeast Asian Studies #Rangeland Management and Livestock Ecology
- Integrating common and rare genetic variation in diverse human populations
2010/08/31 by David Altshuler, S. F. Schaffner, Stacey B. Gabriel +57 · 70 citations
Biochemistry, Genetics and Molecular Biology · #Genomic variations and chromosomal abnormalities #Genomics and Phylogenetic Studies #Genomics and Rare Diseases
- Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores
2015/10/01 by Bjarni J. Vilhjálmsson, Bjarni J. Vilhjálmsson, Jian Yang +452 · 61 citations
Biochemistry, Genetics and Molecular Biology · Mathematics · Medicine · #Advanced Causal Inference Techniques #Allele #Artificial intelligence #Bioinformatics and Genomic Networks #Biology #Computer science #Disequilibrium #Genetic Associations and Epidemiology #Genetics #Haplotype #Linkage disequilibrium #Mathematics #Medicine #Pattern recognition (psychology) #Polygenic risk score #Pruning #Sample (material) #Sample size determination #Single-nucleotide polymorphism #Statistics #Thresholding
- Extreme Polygenicity of Complex Traits Is Explained by Negative Selection
2019/08/08 by Luke J. O'Connor, Luke J. O’Connor, Armin P. Schoech +5 · 41 citations
Biochemistry, Genetics and Molecular Biology · Psychology · #Artificial intelligence #Biology #Computer science #Evolution and Genetic Dynamics #Evolutionary biology #Genetic Associations and Epidemiology #Genetic Mapping and Diversity in Plants and Animals #Psychology #Selection (genetic algorithm)
- The History of African Gene Flow into Southern Europeans, Levantines, and Jews
2011/04/21 by Priya Moorjani, Nick Patterson, Joel N. Hirschhorn +7 · 22 citations
Biochemistry, Genetics and Molecular Biology · #Forensic and Genetic Research #Race, Genetics, and Society #Genetic Associations and Epidemiology #Gene flow #Gene pool #Biology #Biological dispersal #Population #Demography #African descent #Out of africa #Demographic history #Founder effect #Population genetics #Evolutionary biology #Genetics #Genetic variation #Genealogy #Gene #Haplotype #History #Genotype #Genetic diversity
- Disease Heritability Enrichment of Regulatory Elements Is Concentrated in Elements with Ancient Sequence Age and Conserved Function across Species
2019/03/21 by Margaux L.A. Hujoel, Steven Gazal, Farhad Hormozdiari +2 · 28 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Medicine · Nursing · #Aluminum toxicity and tolerance in plants and animals #Biology #Computational biology #Disease #Evolutionary biology #Function (biology) #Genetic Mapping and Diversity in Plants and Animals #Genetics #Heritability #Internal medicine #Medicine #Sequence (biology) #Trace Elements in Health
- A Genomewide Admixture Map for Latino Populations
2007/05/04 by Alkes L. Price, Nick Patterson, Fuli Yu +34 · 5 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #African american #Allele #Allele frequency #Ancestry-informative marker #Biology #Demography #Disease #Ethnology #Evolutionary biology #Gene #Genealogy #Genetic Associations and Epidemiology #Genetic admixture #Genetic genealogy #Genetics #Genomic variations and chromosomal abnormalities #History #Medicine #Molecular Biology Techniques and Applications #Native american #Population #Sociology
- Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data
2022/09/01 by Martin Jinye Zhang, Kangcheng Hou, Kushal K. Dey +14 · 9 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Atherosclerosis and Cardiovascular Diseases #Extracellular vesicles in disease #Single-cell and spatial transcriptomics
- Fast and accurate imputation of summary statistics enhances evidence of functional enrichment
2013/09/12 by Bogdan Pasaniuc, Noah Zaitlen, Huwenbo Shi +7 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · Mathematics · #q-bio.GN #q-bio.PE #q-bio.QM #stat.AP
- Functional Architectures of Local and Distal Regulation of Gene Expression in Multiple Human Tissues
2017/03/23 by Xuanyao Liu, Hilary K. Finucane, Alexander Gusev +10 · 25 citations
Biochemistry, Genetics and Molecular Biology · #Biology #Cell biology #Computational biology #Computer science #Expression (computer science) #Gene #Gene expression #Gene expression and cancer classification #Genetics #Genomics and Chromatin Dynamics #Programming language #RNA Research and Splicing #Regulation of gene expression