Maris A. Cinelli

1. Design, Synthesis, and Biological Evaluation of 14-Substituted Aromathecins as Topoisomerase I Inhibitors
   2008/07/17 by Maris A. Cinelli, Andrew Morrell, Thomas S. Dexheimer +3 · 5 citations
   Biochemistry, Genetics and Molecular Biology · Chemistry · Pharmacology, Toxicology and Pharmaceutics · #Cancer therapeutics and mechanisms #Synthesis and biological activity #Bioactive Compounds and Antitumor Agents
2. The structure–activity relationships of A-ring-substituted aromathecin topoisomerase I inhibitors strongly support a camptothecin-like binding mode
   2010/06/21 by Maris A. Cinelli, Andrew Morrell, Andrew E. Morrell +5 · 1 citation
   Biochemistry, Genetics and Molecular Biology · Medicine · #Antibiotics Pharmacokinetics and Efficacy #Cancer therapeutics and mechanisms #Neutropenia and Cancer Infections
3. Synthesis and biological evaluation of 14-(aminoalkyl-aminomethyl)aromathecins as topoisomerase I inhibitors: Investigating the hypothesis of shared structure–activity relationships
   2009/09/07 by Maris A. Cinelli, Brenda Cordero, Thomas S. Dexheimer +2 · 1 citation
   Biochemistry, Genetics and Molecular Biology · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Bioactive Compounds and Antitumor Agents #Cancer therapeutics and mechanisms #Neutropenia and Cancer Infections